SCHEMBL752448

SCHEMBL752448

O=[N+]([O-])c1ccc(S(=O)(=O)C(Br)(Br)Br)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 0.57
CA1 P00915 8/20 0.57
CA9 Q16790 7/20 0.57
CA12 O43570 5/20 0.57
CA14 Q9ULX7 4/20 0.57
CA5A P35218 4/20 0.57
CA3 P07451 3/20 0.57
CA4 P22748 3/20 0.57
CA6 P23280 3/20 0.57
CA7 P43166 3/20 0.57
CA13 Q8N1Q1 3/20 0.57
CA5B Q9Y2D0 3/20 0.57
MMP1 P03956 1/20 0.52
MMP2 P08253 1/20 0.52
MMP9 P14780 1/20 0.52
MMP8 P22894 1/20 0.52
MMP13 P45452 1/20 0.52
F2 P00734 1/20 0.47
PRSS1 P07477 1/20 0.47
PRSS2 P07478 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL752449 1.00 CA2 (0.57) CA2CA1CA9CA12CA14
SCHEMBL30888176 0.84 CA2 (0.59) CA2CA1CA9CA12CA14
SCHEMBL5018973 0.81 CA2 (0.55) CA2CA1CA9CA12CA14
SCHEMBL11093420 0.81 CA2 (0.55) CA2CA1CA9CA12CA14
SCHEMBL8142887 0.81 CA2 (0.55) CA2CA1CA9CA12CA14
SCHEMBL14354527 0.81 ALDH1A1 (0.50) CA2CA1CA9CA12CA14
SCHEMBL11400266 0.78 CA2 (0.52) CA2CA1CA9CA12CA14
SCHEMBL11410534 0.78 CA2 (0.52) CA2CA1CA9CA12CA14
SCHEMBL1147674 0.77 CA2 (0.61) CA2CA1CA9CA12CA14
SCHEMBL11419996 0.77 CA2 (0.67) CA2CA1CA9CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2213166-B1 Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone THOR GMBH (DE) 2012-03-21 EP claimed
EP-2213166-A1 Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone THOR GmbH (DE) 2010-08-04 EP claimed
EP-0137228-B1 PHOTOPOLYMERIZABLE COMPOSITION FUJI PHOTO FILM CO., LTD. (JP) 1988-10-05 EP claimed
EP-2213166-B1 Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone THOR GMBH (DE) 2012-03-21 EP disclosed
EP-2216372-A1 Compounds for preventing Ghost odour THOR GmbH (DE) 2010-08-11 EP disclosed
EP-2213166-A1 Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone THOR GmbH (DE) 2010-08-04 EP disclosed