Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.55 |
| ▸ | CA1 | P00915 | 6/20 | 0.55 |
| ▸ | CA9 | Q16790 | 6/20 | 0.55 |
| ▸ | CA12 | O43570 | 5/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.55 |
| ▸ | CA5A | P35218 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CA3 | P07451 | 3/20 | 0.55 |
| ▸ | CA4 | P22748 | 3/20 | 0.55 |
| ▸ | CA6 | P23280 | 3/20 | 0.55 |
| ▸ | CA7 | P43166 | 3/20 | 0.55 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30888176 | 0.83 | CA2 (0.59) | CA2CA1CA9CA12CA14 | |
| SCHEMBL22955424 | 0.81 | CA1 (0.49) | CA2CA1CA9CA12CA14 | |
| SCHEMBL752448 | 0.81 | CA2 (0.57) | CA2CA1CA9CA12CA14 | |
| SCHEMBL752449 | 0.81 | CA2 (0.57) | CA2CA1CA9CA12CA14 | |
| SCHEMBL24590337 | 0.80 | KMT2A (0.66) | CA2CA1CA9CA12CA5A | |
| SCHEMBL11093420 | 0.79 | CA2 (0.55) | CA2CA1CA9CA12CA14 | |
| SCHEMBL8142887 | 0.79 | CA2 (0.55) | CA2CA1CA9CA12CA14 | |
| SCHEMBL9190432 | 0.78 | CA1 (0.46) | CA2CA1CA9CA12CA14 | |
| SCHEMBL9194140 | 0.78 | CA1 (0.46) | CA2CA1CA9CA12CA14 | |
| SCHEMBL16940170 | 0.76 | CA1 (0.52) | CA2CA1CA9CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220204497-A1 | NOVEL COMPOUND HAVING ANTICANCER ACTIVITY, AND METHOD FOR PRODUCING SAME | DONGGUK UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2022-06-30 | — | — | US | disclosed |
| US-9216950-B2 | Agonists of Src homology-2 containing protein tyrosine phosphatase-1 and treatment methods using the same | NATIONAL TAIWAN UNIVERSITY (TW) | 2015-12-22 | — | — | US | disclosed |
| US-9216950-B2 | Agonists of Src homology-2 containing protein tyrosine phosphatase-1 and treatment methods using the same | NATIONAL TAIWAN UNIVERSITY (TW) | 2015-12-22 | — | — | US | disclosed |
| US-9090617-B1 | Agonists of Src homology-2 containing protein tyrosine phosphatase-1 and treatment methods using the same | NATIONAL TAIWAN UNIVERSITY (TW) | 2015-07-28 | — | — | US | disclosed |
| US-9090617-B1 | Agonists of Src homology-2 containing protein tyrosine phosphatase-1 and treatment methods using the same | NATIONAL TAIWAN UNIVERSITY (TW) | 2015-07-28 | — | — | US | disclosed |
| US-20150191467-A1 | AGONISTS OF SRC HOMOLOGY-2 CONTAINING PROTEIN TYROSINE PHOSPHATASE-1 AND TREATMENT METHODS USING THE SAME | RAND BIOSCIENCES (KR) | 2015-07-09 | — | — | US | disclosed |
| US-20150191467-A1 | AGONISTS OF SRC HOMOLOGY-2 CONTAINING PROTEIN TYROSINE PHOSPHATASE-1 AND TREATMENT METHODS USING THE SAME | RAND BIOSCIENCES (KR) | 2015-07-09 | — | — | US | disclosed |
| US-20140315784-A1 | Binding Inhibitors of the Beta. Transducin Repeat-Containing Protein | ITI SCOTLAND LIMITED (GB) | 2014-10-23 | — | — | US | disclosed |
| US-20140200239-A1 | AGONISTS OF SRC HOMOLOGY-2 CONTAINING PROTEIN TYROSINE PHOSPHATASE-1 AND TREATMENT METHODS USING THE SAME | NATIONAL TAIWAN UNIVERSITY (TW) | 2014-07-17 | — | — | US | disclosed |
| US-20140200239-A1 | AGONISTS OF SRC HOMOLOGY-2 CONTAINING PROTEIN TYROSINE PHOSPHATASE-1 AND TREATMENT METHODS USING THE SAME | NATIONAL TAIWAN UNIVERSITY (TW) | 2014-07-17 | — | — | US | disclosed |
| WO-2010054102-A2 | POLYBASIC BACTERIAL EFFLUX PUMP INHIBITORS AND THERAPEUTIC USES THEREOF | MPEX PHARMACEUTICALS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |
| US-20090318548-A1 | PARA-QUINOL DERIVATIVES AND METHODS OF STEREO SELECTIVELY SYNTHESIZING AND USING SAME | UNIVERSITY OF NORTHERN BRITISH COLUMBIA (CA) | 2009-12-24 | — | — | US | disclosed |
| US-20090274650-A1 | INHIBITORS OF ASPARTYL PROTEASE | VERTEX PHARMACEUTICALS INCORPORATED | 2009-11-05 | — | — | US | disclosed |
| US-20090274650-A1 | INHIBITORS OF ASPARTYL PROTEASE | VERTEX PHARMACEUTICALS INCORPORATED | 2009-11-05 | — | — | US | disclosed |
| US-20090133747-A1 | COMPOUND HAVING PHOTOSENSITIZATION ACTIVITY, PHOTOELECTRODE, AND PHOTOSENSITIZATION-TYPE SOLAR CELL | CREDIA JAPAN CO., LTD. ( A juridical person under the laws of Japan) (JP) | 2009-05-28 | — | — | US | disclosed |
| US-20080234464-A1 | Compound Having Amino Acid Residue or Peptide Residue and Process for Producing the Same | CREDIA JAPAN CO., LTD. (JP) | 2008-09-25 | — | — | US | disclosed |
| US-20080227826-A1 | Inhibitors of Histone Deacetylase | METHYLGENE INC. (CA) | 2008-09-18 | — | — | US | disclosed |
| US-7244847-B2 | Benzimidazole compounds | ISIS PHARMACEUTICALS, INC. (US) | 2007-07-17 | — | — | US | disclosed |
| US-20070066653-A1 | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof | ASTRAZENECA AB (SE) | 2007-03-22 | — | — | US | disclosed |
| US-20070066653-A1 | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof | ASTRAZENECA AB (SE) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227826-A1 | Inhibitors of Histone Deacetylase | HDAC1, HDAC11, HDAC5 | CA2 1740/4885CA1 1270/4885CA9 1596/4885 |
| US-20070066653-A1 | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof | OPRM1, OPRL1, OPRD1 | CA2 2121/4885CA1 4201/4885CA9 3399/4885 |
| US-20150191467-A1 | AGONISTS OF SRC HOMOLOGY-2 CONTAINING PROTEIN TYROSINE PHOSPHATASE-1 AND TREATMENT METHODS USING THE SAME | SRC, PTPRCAP, GRB2 | CA2 2014/4885CA1 4245/4885CA9 4777/4885 |
| US-20220204497-A1 | NOVEL COMPOUND HAVING ANTICANCER ACTIVITY, AND METHOD FOR PRODUCING SAME | TPX2, AIMP2, CDYL2 | CA2 1511/4885CA1 3749/4885CA9 1248/4885 |
| US-20140200239-A1 | AGONISTS OF SRC HOMOLOGY-2 CONTAINING PROTEIN TYROSINE PHOSPHATASE-1 AND TREATMENT METHODS USING THE SAME | SRC, PTPRCAP, GRB2 | CA2 2014/4885CA1 4245/4885CA9 4777/4885 |
| US-20090318548-A1 | PARA-QUINOL DERIVATIVES AND METHODS OF STEREO SELECTIVELY SYNTHESIZING AND USING SAME | CBR3, XDH, NQO2 | CA2 4166/4885CA1 4031/4885CA9 3966/4885 |
| US-20080234464-A1 | Compound Having Amino Acid Residue or Peptide Residue and Process for Producing the Same | NGLY1, ELOVL6, ELOVL1 | CA2 2507/4885CA1 1005/4885CA9 2059/4885 |
| US-20140315784-A1 | Binding Inhibitors of the Beta. Transducin Repeat-Containing Protein | TARDBP, EPS15, TTC14 | CA2 4703/4885CA1 4811/4885CA9 4739/4885 |
| US-20090274650-A1 | INHIBITORS OF ASPARTYL PROTEASE | SPINT2, DNPEP, PRSS1 | CA2 584/4885CA1 520/4885CA9 1113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.