Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | DUT | P33316 | 2/20 | 0.45 |
| ▸ | TK2 | O00142 | 7/20 | 0.42 |
| ▸ | TK1 | P04183 | 6/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5040791 | 0.79 | MAPK1 (0.50) | KIF11ALOX15CYP2C19ALDH1A1MAPK1 | |
| SCHEMBL9039609 | 0.79 | KIF11 (0.57) | KIF11DUTTK2TK1HRH4 | |
| SCHEMBL11303069 | 0.78 | KIF11 (0.50) | KIF11DUTTK2TK1HRH4 | |
| SCHEMBL2856185 | 0.78 | KIF11 (0.50) | KIF11DUTTK2TK1HRH4 | |
| SCHEMBL8868624 | 0.76 | KIF11 (0.53) | KIF11DUTTK2TK1HRH4 | |
| SCHEMBL15818117 | 0.75 | KIF11 (0.37) | KIF11DUTTK2TK1TSHR | |
| SCHEMBL28250787 | 0.75 | KIF11 (0.47) | KIF11DUTTK2TK1HRH4 | |
| SCHEMBL12268294 | 0.75 | DUT (0.50) | KIF11DUTTK2TK1HRH4 | |
| SCHEMBL913276 | 0.75 | DUT (0.50) | KIF11DUTTK2TK1HRH4 | |
| SCHEMBL913275 | 0.75 | DUT (0.50) | KIF11DUTTK2TK1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970147-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-1-((1S,4R, 5S)-2-FLUORO-4,5-DIHYDROXY-3-HYDROXYMETHYL-CYCLOPENT-2-ENYL)-1H-PYRIMIDIN-2-ONE | Rexahn Pharmaceuticals, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014145807-A1 | PROCESS FOR THE PREPARATION OF 4-AMINO-1-((1S,4R, 5S)-2-FLUORO-4,5-DIHYDROXY-3-HYDROXYMETHYL-CYCLOPENT-2-ENYL)-1H-PYRIMIDIN-2-ONE | REXAHN PHARMACEUTICALS, INC. (US) | 2014-09-18 | — | — | WO | disclosed |
| EP-1173397-A1 | STEREOSPECIFIC METHOD FOR PREPARING 4-HYDOXYALK-1-ENE COMPOUNDS | PPG-Sipsy S.C.A. (FR) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000066519-A1 | STEREOSPECIFIC METHOD FOR PREPARING 4-HYDOXYALK-1-ENE COMPOUNDS | PPG-SIPSY S.C.A. (FR) | 2000-11-09 | — | — | WO | disclosed |