Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | TK2 | O00142 | 9/20 | 0.43 |
| ▸ | TK1 | P04183 | 1/20 | 0.43 |
| ▸ | DUT | P33316 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.37 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9039609 | 0.89 | KIF11 (0.57) | KIF11HRH4TK2TK1DUT | |
| SCHEMBL887487 | 0.82 | SLC6A11 (0.44) | KIF11TK2TK1SLC6A1 | |
| SCHEMBL22708323 | 0.81 | KIF11 (0.53) | KIF11HRH4TK2TK1DUT | |
| SCHEMBL11275984 | 0.77 | KIF11 (0.74) | KIF11HRH4TK2TK1DUT | |
| SCHEMBL7524693 | 0.76 | KIF11 (0.50) | KIF11HRH4TK2TK1DUT | |
| SCHEMBL20032416 | 0.75 | KIF11 (0.50) | KIF11HRH4TK2TK1DUT | |
| SCHEMBL20032440 | 0.75 | KIF11 (0.50) | KIF11HRH4TK2TK1DUT | |
| SCHEMBL2489713 | 0.75 | KIF11 (0.59) | KIF11HRH4TK2TK1DUT | |
| SCHEMBL8389233 | 0.75 | KIF11 (0.59) | KIF11HRH4TK2TK1DUT | |
| SCHEMBL5282316 | 0.75 | KIF11 (0.59) | KIF11HRH4TK2TK1DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989173-B | Imidazole compound, pharmaceutical composition and application thereof | 广州市恒诺康医药科技有限公司 | 2024-03-19 | — | — | CN | disclosed |
| WO-2022184000-A1 | IMIDAZOLE COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 广州市恒诺康医药科技有限公司 | 2022-09-09 | — | — | WO | disclosed |
| CN-114989173-A | Imidazole compound, pharmaceutical composition and application thereof | 广州市恒诺康医药科技有限公司 | 2022-09-02 | — | — | CN | disclosed |
| US-5665746-A | BACTERICIDE | HOFFMANN-LA ROCHE INC. (US) | 1997-09-09 | — | — | US | disclosed |
| US-5594135-A | BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 1997-01-14 | — | — | US | disclosed |
| US-5589473-A | BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 1996-12-31 | — | — | US | disclosed |
| EP-0675122-A2 | Mono or bicyclic DNA gyrase inhibitors | F. HOFFMANN-LA ROCHE AG (CH) | 1995-10-04 | — | — | EP | disclosed |