Nitrous Acid

Nitrous Acid

SCHEMBL7524974

C/C=C/c1c(C2CC2)nc2ccccc2c1-c1ccc(F)cc1.O=NO

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.67
NR1I2 O75469 1/20 0.59
NR4A2 P43354 1/20 0.59
PDE4D Q08499 1/20 0.59
PRKAA2 P54646 1/20 0.57
HMGCR P04035 3/20 0.57
FABP4 P15090 1/20 0.36
FABP5 Q01469 1/20 0.36
TNKS O95271 1/20 0.34
TNKS2 Q9H2K2 1/20 0.34
PARP2 Q9UGN5 1/20 0.34
GRM2 Q14416 1/20 0.34
ALDH1A1 P00352 1/20 0.34
SCN9A Q15858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrous Acid SCHEMBL6665052 1.00 RXRA (0.67) RXRANR1I2NR4A2PDE4DPRKAA2
SCHEMBL10129907 0.93 RXRA (0.68) RXRANR1I2NR4A2PDE4DPRKAA2
SCHEMBL526489 0.93 RXRA (0.68) RXRANR1I2NR4A2PDE4DPRKAA2
SCHEMBL526488 0.93 RXRA (0.68) RXRANR1I2NR4A2PDE4DPRKAA2
SCHEMBL15247428 0.85 RXRA (0.56) RXRANR1I2NR4A2PDE4DPRKAA2
SCHEMBL6283365 0.84 RXRA (0.84) RXRANR1I2NR4A2PDE4DPRKAA2
SCHEMBL6283353 0.84 RXRA (0.84) RXRANR1I2NR4A2PDE4DPRKAA2
SCHEMBL29466456 0.82 RXRA (0.75) RXRANR1I2NR4A2PDE4DPRKAA2
SCHEMBL1844436 0.82 RXRA (0.75) RXRANR1I2NR4A2PDE4DPRKAA2
SCHEMBL1843198 0.82 RXRA (0.75) RXRANR1I2NR4A2PDE4DPRKAA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2002155056-A METHOD FOR PRODUCING QUINOLYLACRYLONITRILE DERIVATIVE UBE IND LTD 2002-05-28 JP disclosed
JP-2001199964-A METHOD FOR PRODUCING QUINOLYLPROPENAL UBE IND LTD 2001-07-24 JP disclosed
JP-2001199963-A METHOD FOR PRODUCING QUINOLYLPROPENAL UBE IND LTD 2001-07-24 JP disclosed