Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.67 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.57 |
| ▸ | HMGCR | P04035 | 3/20 | 0.57 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrous Acid SCHEMBL7524974 | 1.00 | RXRA (0.67) | RXRANR1I2NR4A2PDE4DPRKAA2 | |
| SCHEMBL10129907 | 0.93 | RXRA (0.68) | RXRANR1I2NR4A2PDE4DPRKAA2 | |
| SCHEMBL526489 | 0.93 | RXRA (0.68) | RXRANR1I2NR4A2PDE4DPRKAA2 | |
| SCHEMBL526488 | 0.93 | RXRA (0.68) | RXRANR1I2NR4A2PDE4DPRKAA2 | |
| SCHEMBL15247428 | 0.85 | RXRA (0.56) | RXRANR1I2NR4A2PDE4DPRKAA2 | |
| SCHEMBL6283365 | 0.84 | RXRA (0.84) | RXRANR1I2NR4A2PDE4DPRKAA2 | |
| SCHEMBL6283353 | 0.84 | RXRA (0.84) | RXRANR1I2NR4A2PDE4DPRKAA2 | |
| SCHEMBL29466456 | 0.82 | RXRA (0.75) | RXRANR1I2NR4A2PDE4DPRKAA2 | |
| SCHEMBL1844436 | 0.82 | RXRA (0.75) | RXRANR1I2NR4A2PDE4DPRKAA2 | |
| SCHEMBL1843198 | 0.82 | RXRA (0.75) | RXRANR1I2NR4A2PDE4DPRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030114680-A1 | PROCESS FOR THE PREPARATION OF QUINOLYLPROPENAL | UBE INDUSTRIES LTD (JP) | 2003-06-19 | — | — | US | claimed |
| US-20030013885-A1 | PROCESS FOR PREPARING QUINOLYLACRYLONITRILE AND INTERMEDIATES THEREFOR | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-16 | — | — | US | claimed |
| EP-1251124-A1 | PROCESS FOR THE PREPARATION OF QUINOLYLPROPENAL | Ube Industries, Ltd. (JP) | 2002-10-23 | — | — | EP | claimed |
| EP-1251123-A1 | PROCESS FOR PREPARING QUINOLYLACRYLONITRILE AND INTERMEDIATES THEREFOR | Ube Industries, Ltd. (JP) | 2002-10-23 | — | — | EP | claimed |
| EP-1251123-B1 | PROCESS FOR PREPARING QUINOLYLACRYLONITRILE AND INTERMEDIATES THEREFOR | NISSAN CHEMICAL IND LTD (JP) | 2004-07-21 | — | — | EP | disclosed |
| US-20030114680-A1 | PROCESS FOR THE PREPARATION OF QUINOLYLPROPENAL | UBE INDUSTRIES LTD (JP) | 2003-06-19 | — | — | US | disclosed |
| US-20030114680-A1 | PROCESS FOR THE PREPARATION OF QUINOLYLPROPENAL | UBE INDUSTRIES LTD (JP) | 2003-06-19 | — | — | US | disclosed |
| US-20030013885-A1 | PROCESS FOR PREPARING QUINOLYLACRYLONITRILE AND INTERMEDIATES THEREFOR | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-16 | — | — | US | disclosed |
| US-20030013885-A1 | PROCESS FOR PREPARING QUINOLYLACRYLONITRILE AND INTERMEDIATES THEREFOR | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-16 | — | — | US | disclosed |
| EP-1251124-A1 | PROCESS FOR THE PREPARATION OF QUINOLYLPROPENAL | Ube Industries, Ltd. (JP) | 2002-10-23 | — | — | EP | disclosed |
| EP-1251123-A1 | PROCESS FOR PREPARING QUINOLYLACRYLONITRILE AND INTERMEDIATES THEREFOR | Ube Industries, Ltd. (JP) | 2002-10-23 | — | — | EP | disclosed |
| EP-1251123-A1 | PROCESS FOR PREPARING QUINOLYLACRYLONITRILE AND INTERMEDIATES THEREFOR | Ube Industries, Ltd. (JP) | 2002-10-23 | — | — | EP | disclosed |
| JP-2002155056-A | METHOD FOR PRODUCING QUINOLYLACRYLONITRILE DERIVATIVE | UBE IND LTD | 2002-05-28 | — | — | JP | disclosed |
| US-6335449-B1 | ANTICHOLESTEROL, ENZYME INHIBITOR | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-01 | — | — | US | disclosed |
| JP-2001199964-A | METHOD FOR PRODUCING QUINOLYLPROPENAL | UBE IND LTD | 2001-07-24 | — | — | JP | disclosed |
| JP-2001199962-A | METHOD FOR PRODUCING QUINOLYLACRYLONITRILE AND INTERMEDIATE THEREOF | UBE IND LTD | 2001-07-24 | — | — | JP | disclosed |
| JP-2001199963-A | METHOD FOR PRODUCING QUINOLYLPROPENAL | UBE IND LTD | 2001-07-24 | — | — | JP | disclosed |
| EP-1099694-A1 | PROCESS FOR THE PREPARATION OF QUINOLINE DERIVATIVE AND INTERMEDIATE THEREFOR | Nissan Chemical Industries, Ltd. (JP) | 2001-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013885-A1 | PROCESS FOR PREPARING QUINOLYLACRYLONITRILE AND INTERMEDIATES THEREFOR | WEE2, WEE1, CYP4F11 | RXRA 3421/4885NR1I2 4273/4885NR4A2 2310/4885 |
| US-20030114680-A1 | PROCESS FOR THE PREPARATION OF QUINOLYLPROPENAL | PRDX6, PRDX2, PRDX4 | RXRA 3571/4885NR1I2 4353/4885NR4A2 3713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.