Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529372 | 0.82 | — | — | |
| SCHEMBL28053508 | 0.72 | CA1 (0.32) | CA2CA1 | |
| SCHEMBL2949828 | 0.60 | GAA (0.51) | — | |
| SCHEMBL7527601 | 0.60 | CA2 (0.42) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL19042350 | 0.59 | CA1 (0.48) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL11338159 | 0.58 | CA1 (0.47) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL27868365 | 0.57 | CA2 (0.42) | CA2F2PRSS1PRSS2PRSS3 | |
| SCHEMBL1978683 | 0.57 | — | — | |
| Sulfuric Acid SCHEMBL11494938 | 0.57 | — | — | |
| SCHEMBL22169227 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1185488-A1 | SULPHONYLAMIDES AND CARBOXAMIDES AND THEIR USE IN ASYMMETRICAL CATALYSIS | RHODIA CHIMIE (FR) | 2002-03-13 | — | — | EP | claimed |
| WO-2000076942-A1 | SULPHONYLAMIDES AND CARBOXAMIDES AND THEIR USE IN ASYMMETRICAL CATALYSIS | RHODIA CHIMIE (FR) | 2000-12-21 | — | — | WO | claimed |
| EP-1185488-A1 | SULPHONYLAMIDES AND CARBOXAMIDES AND THEIR USE IN ASYMMETRICAL CATALYSIS | RHODIA CHIMIE (FR) | 2002-03-13 | — | — | EP | disclosed |
| WO-2000076942-A1 | SULPHONYLAMIDES AND CARBOXAMIDES AND THEIR USE IN ASYMMETRICAL CATALYSIS | RHODIA CHIMIE (FR) | 2000-12-21 | — | — | WO | disclosed |