Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4775445 | 0.84 | SMN1; SMN2 (0.54) | GAAALDH1A1KMT2AMAPTACHE | |
| SCHEMBL4775447 | 0.79 | HTR2A (0.38) | GAAMCOLN3ALDH1A1KDM4EMEN1 | |
| SCHEMBL7530799 | 0.76 | MEN1 (0.41) | GAAALDH1A1MEN1KMT2A | |
| SCHEMBL5059654 | 0.75 | KMT2A (0.50) | MCOLN3ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL28053508 | 0.73 | CA1 (0.32) | — | |
| SCHEMBL3193854 | 0.69 | GAA (1.00) | GAAMCOLN3ALDH1A1KMT2APSEN1 | |
| SCHEMBL16877047 | 0.68 | TRPA1 (0.41) | KMT2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL7541549 | 0.67 | GAA (0.96) | GAAMCOLN3ALDH1A1KMT2APSEN1 | |
| SCHEMBL3193960 | 0.67 | GAA (0.96) | GAAMCOLN3ALDH1A1KMT2APSEN1 | |
| SCHEMBL30587708 | 0.67 | MAOB (0.48) | GAAMCOLN3ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104529915-B | Quinokysalines with DNA topoisomerase II inhibiting activities are similar to object and its preparation method and application | 山东大学 | 2018-07-24 | — | — | CN | disclosed |
| US-7754889-B2 | 1,2-di(4-N,N-dimethylaminophenyl)ethylene-1,2-diamine catalyst complex for asymmetric synthesis; for producing an optically active alcohol using the catalyst to asymmetrically reduce a ketone | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-07-13 | — | — | US | disclosed |
| US-20070149831-A1 | 1,2-di(4-N,N-dimethylaminophenyl)ethylene-1,2-diamine catalyst complex for asymmetric synthesis; for producing an optically active alcohol using the catalyst to asymmetrically reduce a ketone | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-06-28 | — | — | US | disclosed |
| WO-2005075073-A1 | WATER-SOLUBLE TRANSITION METAL-DIAMINE COMPLEX AND USE THEREOF | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149831-A1 | 1,2-di(4-N,N-dimethylaminophenyl)ethylene-1,2-diamine catalyst complex for asymmetric synthesis; for producing an optically active alcohol using the catalyst to asymmetrically reduce a ketone | ADH1C, ADH1A, ADH5 | GAA 4417/4885MCOLN3 3065/4885ALDH1A1 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.