Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL752505 | 0.74 | NAALAD2 (0.46) | ALDH1A1EPHX1KDM4CTDP1 | |
| SCHEMBL27966323 | 0.73 | EPHX1 (0.33) | ALDH1A1EPHX1KDM4CL3MBTL1 | |
| SCHEMBL13164954 | 0.71 | ALDH1A1 (0.55) | ALDH1A1EPHX1KDM4CKMT2ATDP1 | |
| SCHEMBL18901899 | 0.68 | EPHX1 (0.35) | ALDH1A1EPHX1 | |
| SCHEMBL7723625 | 0.67 | EPHX1 (0.33) | EPHX1KDM4C | |
| SCHEMBL28109569 | 0.65 | EPHX1 (0.32) | ALDH1A1EPHX1KDM4CKMT2A | |
| SCHEMBL748437 | 0.65 | TSHR (0.44) | ALDH1A1EPHX1KDM4CKMT2A | |
| SCHEMBL20707104 | 0.65 | EPHX1 (0.33) | ALDH1A1EPHX1KMT2ATDP1L3MBTL1 | |
| SCHEMBL27966163 | 0.65 | L3MBTL1 (0.34) | ALDH1A1EPHX1KMT2AL3MBTL1 | |
| SCHEMBL6003046 | 0.65 | FFAR3 (0.35) | ALDH1A1KDM4CKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2400846-A1 | HEPATITIS C VIRUS INHIBITORS | Enanta Pharmaceuticals, Inc. (US) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010099527-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2010-09-02 | — | — | WO | disclosed |