Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 3/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979479 | 0.83 | CTSK (0.45) | TSHRSMN1; SMN2NAALAD2CTSSCTSK | |
| SCHEMBL1979477 | 0.83 | CTSK (0.45) | TSHRSMN1; SMN2NAALAD2CTSSCTSK | |
| SCHEMBL28787095 | 0.83 | TSHR (0.45) | TSHRSMN1; SMN2NAALAD2GAAMGAM | |
| SCHEMBL752505 | 0.83 | NAALAD2 (0.46) | TSHRSMN1; SMN2NAALAD2KDM4CCTSS | |
| SCHEMBL2837383 | 0.83 | CTSK (0.45) | TSHRSMN1; SMN2NAALAD2CTSSCTSK | |
| SCHEMBL751175 | 0.83 | TSHR (0.39) | TSHRSMN1; SMN2NAALAD2KDM4CCTSS | |
| SCHEMBL12987008 | 0.80 | TSHR (0.40) | TSHRSMN1; SMN2NAALAD2KDM4CCTSS | |
| SCHEMBL13544391 | 0.77 | NAALAD2 (0.47) | TSHRSMN1; SMN2NAALAD2KDM4CEPHX1 | |
| SCHEMBL5607969 | 0.77 | NAALAD2 (0.47) | TSHRSMN1; SMN2NAALAD2KDM4CEPHX1 | |
| SCHEMBL13209005 | 0.76 | TSHR (0.45) | TSHRSMN1; SMN2NAALAD2KDM4CCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |