SCHEMBL7525085

SCHEMBL7525085

Oc1cc(OCc2ccccc2)ccc1-n1nc2ccc(Cl)cc2n1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.48
LMNA P02545 1/20 0.42
CYP1A2 P05177 1/20 0.42
PTGS1 P23219 1/20 0.42
SLC6A2 P23975 1/20 0.42
CYP2C19 P33261 1/20 0.42
PTGS2 P35354 1/20 0.42
SLC6A3 Q01959 1/20 0.42
HIF1A Q16665 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
MAOA P21397 2/20 0.41
CYP3A4 P08684 2/20 0.40
ALOX5 P09917 1/20 0.40
HRH4 Q9H3N8 1/20 0.40
KDM4E B2RXH2 1/20 0.40
HSP90AA1 P07900 1/20 0.40
MAPT P10636 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7532670 0.89 LMNA (0.50) MAOBLMNACYP1A2PTGS1SLC6A2
SCHEMBL14017578 0.85 MAOB (0.40) MAOBLMNAHIF1ANPC1RAB9A
SCHEMBL28121989 0.84 DHODH (0.41) LMNACYP1A2CYP2C19NPC1RAB9A
SCHEMBL29492091 0.84 KMT2A (0.46) LMNANPC1RAB9AKDM4EMAPT
SCHEMBL29492032 0.82 PDE2A (0.41) NPC1RAB9AMAPTTDP1
SCHEMBL9639345 0.82 DHODH (0.42) MAOBLMNANPC1RAB9AMAPT
SCHEMBL17940503 0.82 PDE2A (0.41) NPC1RAB9AMAPTTDP1
SCHEMBL9638513 0.80 TRIM24 (0.42) MAOBCYP1A2CYP2C19NPC1RAB9A
SCHEMBL29492118 0.80 TRIM24 (0.42) MAOBCYP1A2CYP2C19NPC1RAB9A
SCHEMBL21586963 0.79 MAOB (0.41) MAOBCYP1A2NPC1RAB9AHRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107974018-A A kind of high durable PMMA film PP Pipe Compounds and its preparation method and application 中国石油化工股份有限公司 2018-05-01 CN claimed
CN-107083052-B Polyamide material and preparation method thereof for welding assembly 深圳市前海宇昕科技有限公司 2019-05-03 CN disclosed
CN-108842932-A A kind of high guarantor's clay soil/polyolefin antiadhesion barrier and preparation method thereof 江苏优珀斯材料科技有限公司 2018-11-20 CN disclosed
CN-108264858-A A kind of new A B glue being bonded for acryl plates and preparation method thereof 浙江天和树脂有限公司 2018-07-10 CN disclosed
CN-106634702-A Snail track-resistant POE solar energy packaging adhesive film and preparation method thereof 宁波华顺太阳能科技有限公司 2017-05-10 CN disclosed
CN-106366549-A Resin frame, preparation method, and application thereof 宁波华顺太阳能科技有限公司 2017-02-01 CN disclosed
EP-0661401-B1 Agent for treating textile materials NICCA CHEMICAL CO (JP) 2002-03-20 EP disclosed
US-5516436-A Agent for treating textile materials NICCA CHEMICAL CO., LTD. (JP) 1996-05-14 US disclosed
EP-0661401-A2 Agent for treating textile materials NICCA CHEMICAL CO., LTD. (JP) 1995-07-05 EP disclosed