SCHEMBL21586963

SCHEMBL21586963

CC(C)(C)c1cc(OCc2ccccc2)cc(-n2nc3ccc(Cl)cc3n2)c1O

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.41
HRH4 Q9H3N8 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
ESRRA P11474 1/20 0.37
PTGER1 P34995 7/20 0.36
CYP1A1 P04798 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP19A1 P11511 1/20 0.35
ACLY P53396 1/20 0.35
CYP2C9 P11712 1/20 0.35
AR P10275 1/20 0.34
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13021504 0.88 MAOB (0.46) MAOBESRRACYP1A2CYP2C9
SCHEMBL25990439 0.84 ESRRA (0.35) MAOBNPC1RAB9AESRRACYP1A1
SCHEMBL21586945 0.84 CYP1A1 (0.36) ESRRACYP1A1CYP1A2CYP19A1
SCHEMBL21586947 0.83 PDE2A (0.36) NPC1RAB9ACYP1A2CYP2C9
SCHEMBL21586951 0.83 PDE2A (0.35) NPC1RAB9A
SCHEMBL30887157 0.83 PDE2A (0.36) NPC1RAB9ACYP1A2CYP2C9
SCHEMBL23636566 0.83 KDM4E (0.35) MAOBNPC1RAB9AESRRACYP1A1
SCHEMBL12199840 0.82 CA1 (0.48) NPC1RAB9A
SCHEMBL23645034 0.82 NPC1 (0.44) MAOBNPC1RAB9AESRRACYP1A2
SCHEMBL23636564 0.81 ACSS2 (0.37) ESRRACYP1A1CYP1A2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3578550-B1 NOVEL RED-SHIFTING BENZOTRIAZOLE UV ABSORBERS EVERLIGHT CHEM IND CORP (TW) 2023-08-16 EP disclosed
EP-3848357-B1 REACTIVE BENZOTRIAZOLE UV ABSORBER AND USE THEREOF EVERLIGHT CHEM IND CORP (TW) 2023-01-18 EP disclosed
US-20210214321-A1 NOVEL REACTIVE BENZOTRIAZOLE UV ABSORBER AND USE THEREOF EVERLIGHT CHEMICAL INDUSTRIAL CORPORATION (TW) 2021-07-15 US disclosed
EP-3848357-A1 REACTIVE BENZOTRIAZOLE UV ABSORBER AND USE THEREOF Everlight Chemical Industrial Corporation (TW) 2021-07-14 EP disclosed
EP-3578550-A1 NOVEL BENZOTRIAZOLE UV ABSORBER WITH RED SHIFT AND USE THEREOF Everlight Chemical Industrial Corporation (TW) 2019-12-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210214321-A1 NOVEL REACTIVE BENZOTRIAZOLE UV ABSORBER AND USE THEREOF SULT1A1, XDH, SULT2A1 MAOB 237/4885HRH4 862/4885NPC1 4155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.