SCHEMBL7525261

SCHEMBL7525261

Cc1cc(C)c(C(Cl)(Cl)Cl)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 12/20 0.39
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32
TSHR P16473 1/20 0.32
HTT P42858 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TP53 P04637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4586493 0.78 RAPGEF4 (0.36) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL8388461 0.73 ALDH1A1 (0.42) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL22914917 0.73 ALDH1A1 (0.42) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL1227758 0.73 RAPGEF4 (0.41) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL27713988 0.71 HTT (0.37) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL28228647 0.71 RAPGEF4 (0.39) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL2121908 0.71 RAPGEF4 (0.39) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL10994353 0.71 RAPGEF4 (0.43) RAPGEF4ALDH1A1KDM4ELMNAGAA
SCHEMBL12597845 0.69 L3MBTL1 (0.43) RAPGEF4ALDH1A1LMNAMAPTTSHR
SCHEMBL18535704 0.69 ALDH1A1 (0.39) RAPGEF4ALDH1A1KDM4ELMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117209360-A Preparation method of antioxidant 330 上海齐润新材料有限公司 2023-12-12 CN claimed
CN-116199612-A Porous adsorbent and preparation method and application thereof 荆楚理工学院 2023-06-02 CN claimed
CN-115926334-A Porous polymer hydrogen storage material and preparation method thereof 上海超高环保科技股份有限公司 2023-04-07 CN claimed
CN-115093585-A Waste plastic-based super-crosslinked polymer prepared from waste polystyrene plastic, and preparation method and application thereof 兰州石化职业技术学院 2022-09-23 CN claimed
CN-115073523-A Preparation method and application of ionic type antimonide luminescent material with large steric hindrance 中国计量大学 2022-09-20 CN claimed
CN-111943838-A Preparation method of 2,4, 6-trimethylbenzoyl chloride and acyl chloride co-production technology 深圳有为技术控股集团有限公司 2020-11-17 CN claimed
CN-110872320-A Condensation reaction of mesityloyl halide and diphenylphosphine oxide and preparation of organophosphine compound 深圳有为技术控股集团有限公司 2020-03-10 CN claimed
CN-107398259-A Volatile organic matter adsorbent for industrial waste gas processing 德阳护球环保科技有限公司 2017-11-28 CN claimed
US-9610533-B2 Organo-amine acid gas adsorption-desorption polymers, processes for preparing same, and uses thereof EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2017-04-04 US claimed
CN-102875598-B (diphenyl phosphinyl groups) (mesitylene base) ketone and the preparation method of (phosphniline epoxide) double (mesitylene base ketone) 深圳市有为化学技术有限公司 2016-09-07 CN claimed
US-20150307661-A1 ORGANO-AMINE ACID GAS ADSORPTION-DESORPTION POLYMERS, PROCESSES FOR PREPARING SAME, AND USES THEREOF EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2015-10-29 US claimed
US-9169370-B2 Polyvinyl-amine acid gas adsorption-desorption polymers, processes for preparing same, and uses thereof EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2015-10-27 US claimed
US-9115260-B2 Organo-amine acid gas adsorption-desorption polymers, processes for preparing same, and uses thereof EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2015-08-25 US claimed
CN-103657610-A Porous polymer adsorbent for selectively adsorbing carbon dioxide and preparation method thereof NANJING UNIVERSITY OF TECHNOLOGY 2014-03-26 CN claimed
US-8557027-B2 Epoxy-amine acid gas adsorption-desorption polymers and oligomers, processes for preparing same, and uses thereof EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2013-10-15 US claimed
CN-102875598-A Preparation method of (diphenylphosphine oxide)(mesitylene)ketone and (phenylphosphine oxide)bis(mesitylene ketone) CHEN TING 2013-01-16 CN claimed
US-20120164045-A1 Polyvinyl-Amine Acid Gas Adsorption-Desorption Polymers, Processes for Preparing Same, and Uses Thereof EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-06-28 US claimed
US-20120164043-A1 Organo-Amine Acid Gas Adsorption-Desorption Polymers, Processes for Preparing Same, and Uses Thereof EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-06-28 US claimed
US-20120160097-A1 Epoxy-Amine Acid Gas Adsorption-Desorption Polymers and Oligomers, Processes for Preparing Same, and Uses Thereof EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2012-06-28 US claimed
US-4448935-A CHLORO, BROMO OR HYDROXY AROMATIC CROSSLINKING AGENTS NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1984-05-15 US claimed