Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 6/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.43 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CDK4 | P11802 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PAK4 | O96013 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3299538 | 0.81 | CDK2 (0.45) | CDK1CCNB1CDK5CDK5R1MAPK1 | |
| SCHEMBL3298664 | 0.80 | CDK2 (0.44) | CDK1CCNB1CDK5CDK5R1MAPK1 | |
| SCHEMBL4484465 | 0.76 | CDK2 (0.43) | CDK1CCNB1CDK5CDK5R1KDM4E | |
| SCHEMBL5749121 | 0.74 | CDK1 (0.70) | CDK1CCNB1CCNB2CCNB3EIF2AK2 | |
| SCHEMBL7525338 | 0.73 | HTT (0.67) | CDK1CCNB1CCNB2CCNB3EIF2AK2 | |
| SCHEMBL3859248 | 0.72 | CDK2 (0.58) | CDK1CCNB1CDK5CDK5R1MAPK1 | |
| SCHEMBL3295975 | 0.72 | CDK2 (0.66) | CDK1CCNB1CCNB2CCNB3CDK5 | |
| SCHEMBL7525334 | 0.72 | CDK1 (0.53) | CDK1CCNB1CCNB2CCNB3EIF2AK2 | |
| SCHEMBL1293109 | 0.71 | CDK2 (0.49) | CDK1CCNB1CDK5CDK5R1KDM4E | |
| SCHEMBL31707890 | 0.71 | CDK2 (0.49) | CDK1CCNB1CDK5CDK5R1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020103161-A1 | Novel heterocycles | ARIAD PHARMACEUTICALS, INC. | 2002-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020103161-A1 | Novel heterocycles | BMP2, SOST, BMP4 | CDK1 93/4885CCNB1 973/4885CCNB2 451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.