Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.58 |
| ▸ | CTSK | P43235 | 10/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.57 |
| ▸ | CTSB | P07858 | 4/20 | 0.56 |
| ▸ | CTSL | P07711 | 2/20 | 0.55 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.54 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7152899 | 0.94 | CTSS (0.67) | CTSSCTSKLCKCTSBCTSL | |
| SCHEMBL7522969 | 0.88 | CTSS (0.56) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL15800056 | 0.88 | CTSS (0.56) | CTSSCTSKLCKCTSBCTSL | |
| SCHEMBL12972258 | 0.87 | CTSS (0.55) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL4653261 | 0.87 | CTSS (0.54) | CTSSCTSKLCKCTSBCTSL | |
| SCHEMBL30829409 | 0.85 | ACE (0.60) | CTSSCTSKCTSBCTSL | |
| SCHEMBL1172086 | 0.85 | ACE (0.60) | CTSSCTSKCTSBCTSL | |
| SCHEMBL4786137 | 0.85 | ACE (0.60) | CTSSCTSKCTSBCTSL | |
| SCHEMBL8364977 | 0.85 | CTSS (0.51) | CTSSCTSKLCKCTSBCTSL | |
| SCHEMBL3013717 | 0.84 | LCK (0.64) | CTSSCTSKLCKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165492-A1 | HYDROXYPHENYL DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES | Pharmacor Inc. (CA) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059867-A1 | HYDROXYPHENYL DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES | PHARMACOR INC. (CA) | 2000-10-12 | — | — | WO | disclosed |