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Sugi Predict / Compounds / SCHEMBL4786137

SCHEMBL4786137

SCHEMBL4786137

CC(C)(C)OC(=O)NC(Cc1ccc(O)c(O)c1)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 2/20 0.60
▸ ITGB3 P05106 2/20 0.57
▸ ITGA2B P08514 2/20 0.57
▸ PTPN1 P18031 1/20 0.54
▸ CTSS P25774 7/20 0.54
▸ CTSK P43235 6/20 0.54
▸ MME P08473 1/20 0.53
▸ PPARA Q07869 5/20 0.52
▸ PPARG P37231 4/20 0.52
▸ CA1 P00915 2/20 0.52
▸ CA2 P00918 2/20 0.52
▸ CTSB P07858 3/20 0.52
▸ PPARD Q03181 2/20 0.50
▸ ITGB1 P05556 1/20 0.50
▸ ITGAV P06756 1/20 0.50
▸ ITGB5 P18084 1/20 0.50
▸ CTSL P07711 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30829409 1.00 ACE (0.60) ACEITGB3ITGA2BPTPN1CTSS
SCHEMBL1172086 1.00 ACE (0.60) ACEITGB3ITGA2BPTPN1CTSS
SCHEMBL31525018 0.99 ACE (0.59) ACEITGB3ITGA2BPTPN1CTSS
SCHEMBL23069526 0.91 CTSS (0.63) ACEITGB3ITGA2BPTPN1CTSS
SCHEMBL23069525 0.91 CTSS (0.63) ACEITGB3ITGA2BPTPN1CTSS
SCHEMBL13286814 0.90 ACE (0.58) ACEITGB3ITGA2BPTPN1CTSS
SCHEMBL15565481 0.90 ACE (0.58) ACEITGB3ITGA2BPTPN1CTSS
SCHEMBL8364977 0.90 CTSS (0.51) ACEITGB3ITGA2BCTSSCTSK
SCHEMBL23575043 0.89 ACE (0.57) ACEITGB3ITGA2BPTPN1CTSS
SCHEMBL15109826 0.89 CA2 (0.61) ACEITGB3ITGA2BPTPN1CTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 — — EP disclosed
US-12037354-B2 Cyclic pantetheine derivatives and uses thereof VECTIVBIO COMET AG (CH) 2024-07-16 — — US disclosed
US-11904014-B2 Immunostimulatory compositions Assistance Publique—Hopitaux de Paris (FR) 2024-02-20 — — US disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 — — US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 — — CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 — — WO disclosed
US-20230107216-A1 PANTETHEINE DERIVATIVES AND USES THEREOF VECTIVBIO COMET AG, F/K/A COMET THERAPEUTICS, INC. (CH) 2023-04-06 — — US disclosed
US-20230072313-A1 CYCLIC PANTETHEINE DERIVATIVES AND USES THEREOF VECTIVBIO COMET AG, F/K/A COMET THERAPEUTICS, INC. (CH) 2023-03-09 — — US disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed
US-20140187630-A1 NOVEL COMPOUND AND MEDICAL USE THEREOF ONO PHARMACEUTICALS CO., LTD. (JP) 2014-07-03 — — US disclosed
US-8748485-B2 Compound and medical use thereof ONO PHARMACEUTICALS CO., LTD. (JP) 2014-06-10 — — US disclosed
US-8703816-B2 — — 2014-04-22 — — US disclosed
EP-2647619-A1 NOVEL COMPOUND AND MEDICAL USE THEREOF Ono Pharmaceutical Co., Ltd. (JP) 2013-10-09 — — EP disclosed
US-20130245074-A1 NOVEL COMPOUND AND MEDICAL USE THEREOF ONO PHARMACEUTICALS CO., LTD. (JP) 2013-09-19 — — US disclosed
WO-2008079387-A1 CATECHOL PROTECTED LEVODOPA DIESTER PRODRUGS, COMPOSITIONS, AND METHODS OF USE XENOPORT, INC. (US) 2008-07-03 — — WO disclosed
US-6362165-B1 Hydroxyphenyl derivatives with HIV integrase inhibitory properties PHARMACOR INC. (CA) 2002-03-26 — — US disclosed
EP-1030853-A1 NOVEL SIGNAL TRANSDUCTION INHIBITORS, COMPOSITIONS CONTAINING THEM ARIAD PHARMACEUTICALS, INC. (US) 2000-08-30 — — EP disclosed
WO-1999024442-A1 NOVEL SIGNAL TRANSDUCTION INHIBITORS, COMPOSITIONS CONTAINING THEM ARIAD PHARMACEUTICALS, INC. (US) 1999-05-20 — — WO disclosed
CN-1192746-A Peptide derivatives and angiotensin IV receptor agonists SAGAMI CHEM RES (JP) 1998-09-09 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140187630-A1 NOVEL COMPOUND AND MEDICAL USE THEREOF COMT, PARK7, SLC6A3 ACE 1065/4885ITGB3 4654/4885ITGA2B 4464/4885
US-20230107216-A1 PANTETHEINE DERIVATIVES AND USES THEREOF VNN1, NQO1, VKORC1 ACE 1448/4885ITGB3 1543/4885ITGA2B 1701/4885
US-20130245074-A1 NOVEL COMPOUND AND MEDICAL USE THEREOF COMT, PARK7, SLC6A3 ACE 1065/4885ITGB3 4654/4885ITGA2B 4464/4885
US-20230072313-A1 CYCLIC PANTETHEINE DERIVATIVES AND USES THEREOF VNN1, VKORC1, PANK3 ACE 2375/4885ITGB3 1547/4885ITGA2B 1803/4885
US-12037354-B2 Cyclic pantetheine derivatives and uses thereof VNN1, VKORC1, PANK3 ACE 2375/4885ITGB3 1547/4885ITGA2B 1803/4885
US-11904014-B2 Immunostimulatory compositions CD47, CD74, LY96 ACE 3860/4885ITGB3 1349/4885ITGA2B 764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.