Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.54 |
| ▸ | CTSK | P43235 | 10/20 | 0.54 |
| ▸ | CTSB | P07858 | 4/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7525536 | 0.87 | CTSS (0.58) | CTSSCTSKCTSBCTSLLCK | |
| SCHEMBL4382913 | 0.86 | CTSS (0.70) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL1172086 | 0.86 | ACE (0.60) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL8364977 | 0.86 | CTSS (0.51) | CTSSCTSKCTSBCTSLLCK | |
| SCHEMBL4786137 | 0.86 | ACE (0.60) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL30829409 | 0.86 | ACE (0.60) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL4118607 | 0.85 | REN (0.52) | CTSSCTSKCTSBCTSLLCK | |
| SCHEMBL3013721 | 0.85 | LCK (0.64) | CTSSCTSKCTSBCTSLLCK | |
| SCHEMBL31525018 | 0.85 | ACE (0.59) | CTSSCTSKCTSBACE | |
| SCHEMBL3013717 | 0.85 | LCK (0.64) | CTSSCTSKCTSBCTSLLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1993995-A1 | AMINO ACID DERIVATIVES | Proximagen Ltd. (GB) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007104959-A1 | AMINO ACID DERIVATIVES | PROXIMAGEN LTD. (GB) | 2007-09-20 | — | — | WO | disclosed |