Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24753529 | 0.82 | LMNA (0.47) | LMNAGPR84CYP2D6SPHK1GMNN | |
| SCHEMBL4814498 | 0.81 | LMNA (0.45) | LMNAGPR84CYP2D6SPHK1GMNN | |
| SCHEMBL27212653 | 0.79 | LMNA (0.44) | LMNAGPR84CYP2D6SPHK1GMNN | |
| SCHEMBL118048 | 0.79 | LMNA (0.44) | LMNAGPR84CYP2D6SPHK1GMNN | |
| SCHEMBL27892823 | 0.76 | LMNA (0.52) | LMNAGPR84CYP2D6SPHK1GMNN | |
| SCHEMBL25293444 | 0.76 | GPR84 (0.52) | LMNAGPR84SPHK1PLA2G1BPLA2G2A | |
| SCHEMBL16390557 | 0.74 | LMNA (0.50) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL7769582 | 0.74 | LMNA (0.45) | LMNACYP2D6SPHK1GMNNPOLB | |
| SCHEMBL21701061 | 0.74 | LMNA (0.55) | LMNAGPR84CYP2D6SPHK1GMNN | |
| SCHEMBL5865607 | 0.73 | LMNA (0.48) | LMNACYP2D6SPHK1GMNNPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0770593-B1 | TRIS(3-AMINOPROPYL)AMINE DERIVATIVE AND DETERGENT COMPOSITION CONTAINING THE SAME | KAO CORP (JP) | 2002-04-03 | — | — | EP | disclosed |
| US-5696071-A | Tris (3-aminopropyl)amine derivative and detergent composition containing the same | KAO CORPORATION (JP) | 1997-12-09 | — | — | US | disclosed |
| EP-0770593-A1 | TRIS(3-AMINOPROPYL)AMINE DERIVATIVE AND DETERGENT COMPOSITION CONTAINING THE SAME | Kao Corporation (JP) | 1997-05-02 | — | — | EP | disclosed |