SCHEMBL7525865

SCHEMBL7525865

CC(C)(C)OC(=O)CCCC(=O)CC#N

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
TSHR P16473 2/20 0.34
EPHX2 P34913 1/20 0.34
CTSK P43235 7/20 0.33
CTSS P25774 6/20 0.33
GLA P06280 1/20 0.32
MCL1 Q07820 2/20 0.31
CTSL P07711 1/20 0.31
CTSB P07858 1/20 0.31
HDAC8 Q9BY41 2/20 0.30
HDAC3 O15379 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1639757 0.80 TSHR (0.50) MEN1KMT2ATSHREPHX2HDAC8
SCHEMBL28508164 0.79 MCL1 (0.39) ALDH1A1MEN1MAPTKMT2ACTSK
SCHEMBL182386 0.78 ALDH1A1 (0.41) ALDH1A1MEN1MAPTKMT2ACTSK
Hydrochloric Acid SCHEMBL7239543 0.78 TSHR (0.48) MEN1KMT2ATSHREPHX2HDAC8
SCHEMBL9847857 0.77 TSHR (0.39) ALDH1A1TSHREPHX2CTSKHDAC8
SCHEMBL11931439 0.77 TDP1 (0.53) MEN1KMT2ACTSKCTSSCTSL
SCHEMBL9585490 0.76 EPHX2 (0.40) MEN1MAPTKMT2AEPHX2CTSK
SCHEMBL28458032 0.76 CTSK (0.36) ALDH1A1MEN1MAPTKMT2ACTSK
SCHEMBL134923 0.76 EPHX2 (0.46) ALDH1A1TSHREPHX2HDAC8HDAC3
SCHEMBL11931441 0.76 TDP1 (0.55) MEN1KMT2ACTSKCTSSCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2002030060-A METHOD FOR PRODUCING 4-CYANO-3-HYDROXYBUTYRIC ACID ESTER WARNER LAMBERT CO 2002-01-29 JP disclosed