Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847789 | 0.87 | TDP1 (0.39) | TSHREPHX2TDP1ALDH1A1HDAC8 | |
| SCHEMBL1639757 | 0.87 | TSHR (0.50) | TSHREPHX2TDP1HDAC8HDAC1 | |
| SCHEMBL2394511 | 0.85 | TSHR (0.44) | TSHREPHX2TDP1ALDH1A1HDAC8 | |
| Hydrochloric Acid SCHEMBL7239543 | 0.84 | TSHR (0.48) | TSHREPHX2TDP1HDAC8HDAC1 | |
| SCHEMBL9847901 | 0.84 | TSHR (0.37) | TSHRTDP1ALDH1A1DGKACYP1A2 | |
| SCHEMBL134923 | 0.82 | EPHX2 (0.46) | TSHREPHX2TDP1ALDH1A1HDAC8 | |
| SCHEMBL2394516 | 0.82 | ALDH1A1 (0.48) | TSHREPHX2ALDH1A1DGKACTSK | |
| SCHEMBL1003368 | 0.80 | CES1 (0.46) | TSHREPHX2ALDH1A1DGKACTSK | |
| SCHEMBL25133062 | 0.80 | MAPT (0.53) | TSHRTDP1ALDH1A1DGKALMNA | |
| SCHEMBL28037931 | 0.80 | MAPT (0.44) | TSHREPHX2ALDH1A1HDAC8HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239787-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2024-07-18 | — | — | US | disclosed |
| US-7342014-B2 | Diamine derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-03-11 | — | — | US | disclosed |
| EP-0457103-A1 | Mixtures of polyamides with aromatic (co)poly(ester)-carbonates based on tertiary alkyl ester groups containing bisphenols | BAYER AG (DE) | 1991-11-21 | — | — | EP | disclosed |
| EP-0457102-A2 | Bisphenols with a tertiary alkyle ester function, their process of preparation and their use | BAYER AG (DE) | 1991-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239787-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | BRIX1, TP53, XPOT | TSHR 2641/4885EPHX2 3230/4885TDP1 3480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.