Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 1/20 | 0.30 |
| ▸ | TERT | O14746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7527648 | 0.85 | — | — | |
| SCHEMBL7523714 | 0.80 | HTT (0.32) | — | |
| SCHEMBL4670884 | 0.79 | KDM1A (0.35) | HIF1AEDNRA | |
| SCHEMBL7527650 | 0.78 | — | — | |
| SCHEMBL7119512 | 0.78 | KDM1A (0.39) | HIF1AEDNRA | |
| SCHEMBL5264237 | 0.74 | CYP1A2 (0.41) | POLBHTR2A | |
| Benzene SCHEMBL7254417 | 0.74 | AKR1C3 (0.34) | HIF1A | |
| SCHEMBL5615531 | 0.74 | ALDH1A1 (0.43) | HIF1AEDNRA | |
| SCHEMBL8140932 | 0.74 | HIF1A (0.30) | HIF1A | |
| SCHEMBL7723531 | 0.73 | CYP11B1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037885-B1 | NOVEL WATER SOLUBLE PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2002-03-27 | — | — | EP | claimed |
| EP-1037885-B1 | NOVEL WATER SOLUBLE PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2002-03-27 | — | — | EP | disclosed |