Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16090076 | 0.90 | CA12 (0.46) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL3468211 | 0.85 | CA12 (0.57) | CA12CA9CA2TSHRMAPK1 | |
| Fluoride SCHEMBL29204690 | 0.82 | CA12 (0.55) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL11512418 | 0.82 | CA12 (0.46) | CA12CA9CA2ALDH1A1CA1 | |
| SCHEMBL11412702 | 0.81 | CA12 (0.48) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL19570764 | 0.80 | CA12 (0.48) | CA12CA9CA2ALDH1A1CA1 | |
| SCHEMBL11527911 | 0.79 | CA12 (0.46) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL3468531 | 0.78 | CA12 (0.50) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL14617689 | 0.78 | ALDH1A1 (0.39) | CA12CA9CA2TSHRMAPK1 | |
| SCHEMBL1526065 | 0.78 | MAPT (0.43) | CA12CA9CA2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1102145-C | Process for the prepn. of N, N'-subistituted ureas | NOVARTIS AG (CH) | 2003-02-26 | — | — | CN | disclosed |
| EP-0873989-B1 | Process for the preparation of distyryl-biphenyl compounds | CIBA SC HOLDING AG (CH) | 2002-03-20 | — | — | EP | disclosed |
| EP-0849244-B1 | Process for the preparation of distyryl-biphenylic compounds | CIBA SC HOLDING AG (CH) | 2001-06-20 | — | — | EP | disclosed |
| US-6031126-A | Process | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-02-29 | — | — | US | disclosed |
| US-5969204-A | Process for the production of distyryl-biphenyl compounds | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-10-19 | — | — | US | disclosed |
| US-5952524-A | Process | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-09-14 | — | — | US | disclosed |
| CN-1225361-A | Process for the prepn. of N, N'-subistituted ureas | NOVARTIS AG (CH) | 1999-08-11 | — | — | CN | disclosed |
| CN-1043889-C | Process for preparing substituted benzenes and benzenesulfonic acids and derivatives thereof | NORVARTIS CORP (CH) | 1999-06-30 | — | — | CN | disclosed |
| CN-1198435-A | Method for producing fluorescent whitening agent | CIBA GEIGY AG (CH) | 1998-11-11 | — | — | CN | disclosed |
| CN-1197065-A | Process for production of distyryl-biphenyl fluorescent whitening agents | CIBA SC HOLDING AG (CH) | 1998-10-28 | — | — | CN | disclosed |
| US-5508402-A | Process for the preparation of N,N'-substituted ureas | CIBA-GEIGY CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |
| EP-0552586-B1 | Process for the production of cyclopropylmethylketone | CIBA GEIGY AG (CH) | 1995-09-20 | — | — | EP | disclosed |
| CN-1083480-A | Process for preparing substituted benzene or benzenesulfonic acid and derivatives thereof and process for preparing N, N' -substituted ureas | CIBA GEIGY AG (US) | 1994-03-09 | — | — | CN | disclosed |
| EP-0584043-A1 | Process for the preparation of substituted benzenes and benzene sulfonic acid and derivatives thereof and a process for the preparation of N'N-substituted ureas | CIBA-GEIGY AG (CH) | 1994-02-23 | — | — | EP | disclosed |
| US-5254739-A | Heating a-acetylbutyrolactone in presence of a halide | CIBA-GEIGY CORPORATION (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0296864-B1 | PROCESS FOR PREPARING UREAS | DOWELANCO (US) | 1993-09-15 | — | — | EP | disclosed |
| EP-0552586-A1 | Process for the production of cyclopropylmethylketone | CIBA-GEIGY AG (CH) | 1993-07-28 | — | — | EP | disclosed |
| US-4987233-A | Process for preparing herbicidal ureas and insecticidal carbamates and carbamate derivatives | ELI LILLY AND COMPANY (US) | 1991-01-22 | — | — | US | disclosed |
| EP-0296864-A2 | Process for preparing ureas | DOWELANCO (US) | 1988-12-28 | — | — | EP | disclosed |
| US-4156769-A | Process for making polycarbonates using 1,1-dimethyl urea compounds as the catalysts | THE DOW CHEMICAL COMPANY (US) | 1979-05-29 | — | — | US | disclosed |