Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19171663 | 0.87 | ALDH1A1 (0.45) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL21901064 | 0.83 | TSHR (0.39) | MAPTALDH1A1TSHRCHRNB2CHRNA4 | |
| SCHEMBL193410 | 0.82 | CA12 (0.43) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL14557535 | 0.81 | MAPT (0.41) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL9682862 | 0.81 | MAPT (0.41) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL7526100 | 0.78 | CA12 (0.50) | CA12CA1CA2CA9ALDH1A1 | |
| Trolamine SCHEMBL28177540 | 0.78 | MAPT (0.43) | MAPTALDH1A1TSHRCHRNB2CHRNA4 | |
| SCHEMBL4508037 | 0.76 | LMNA (0.56) | CA12CA9ALDH1A1 | |
| SCHEMBL9683654 | 0.72 | ALDH1A1 (0.50) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL17471608 | 0.72 | ALDH1A1 (0.44) | MAPTCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12042550-B2 | Leave-on hair treatment compositions | L'OREAL (FR) | 2024-07-23 | — | — | US | claimed |
| US-20240122821-A1 | LEAVE-ON HAIR TREATMENT COMPOSITIONS | L'OREAL (FR) | 2024-04-18 | — | — | US | claimed |
| WO-2024073637-A1 | LEAVE-ON HAIR TREATMENT COMPOSITIONS | L'OREAL (FR) | 2024-04-04 | — | — | WO | claimed |
| EP-1965757-B1 | COSMETIC USE OF A HYDROXYALKYLUREA AS AN AGENT FOR TREATING DESQUAMATIVE CONDITIONS OF THE SCALP; COSMETIC TREATMENT COMPOSITIONS AND PROCESSES | ORÉAL L (FR) | 2016-11-23 | — | — | EP | claimed |
| EP-1743623-B1 | Use of urea compounds for promoting desquamation | ORÉAL L (FR) | 2016-06-29 | — | — | EP | claimed |
| EP-1674072-B1 | Use of urea compounds to combat indications of skin ageing | ORÉAL L (FR) | 2014-06-04 | — | — | EP | claimed |
| US-8173144-B2 | Administration of urea compounds for combating signs of cutaneous aging | L'OREAL (FR) | 2012-05-08 | — | — | US | claimed |
| US-7999008-B2 | Urea compounds that promote desquamation | L'OREAL (FR) | 2011-08-16 | — | — | US | claimed |
| EP-1661550-B1 | Cosmetic and/or dermatological composition comprising urea compound | OREAL (FR) | 2011-04-27 | — | — | EP | claimed |
| EP-1824447-B1 | COSMETIC COMPOSITION COMPRISING A TENSIONING AGENT AND A HYDROXYALKYL UREA | OREAL (FR) | 2010-06-09 | — | — | EP | claimed |
| EP-1702609-A1 | Cosmetic cleansing composition comprising a urea derivative and a polymer | L'OREAL (FR) | 2006-09-20 | — | — | EP | claimed |
| US-20060193813-A1 | Nanoemulsion containing a hydroxylated urea compound | L'OREAL (FR) | 2006-08-31 | — | — | US | claimed |
| US-20060177395-A1 | Sunscreen compositions comprising hydrophilic UV-screening agents and hydroxyalkylurea compounds | L'OREAL (FR) | 2006-08-10 | — | — | US | claimed |
| US-20060177393-A1 | Sunscreen compositions comprising lipophilic UV-screening agents and hydroxyalkylurea compounds | L'OREAL (FR) | 2006-08-10 | — | — | US | claimed |
| US-20060177397-A1 | Self-tanning product comprising two components and means for artificially coloring the skin | L'OREAL (FR) | 2006-08-10 | — | — | US | claimed |
| US-20060177396-A1 | Sunscreen compositions comprising metal oxide mineral pigments and hydroxyalkylurea compounds | L'OREAL (FR) | 2006-08-10 | — | — | US | claimed |
| US-20060177394-A1 | Sunscreen compositions comprising insoluble organic UV-screening agents and hydroxyalkylurea compounds | L'OREAL (FR) | 2006-08-10 | — | — | US | claimed |
| WO-2006056491-A1 | COSMETIC COMPOSITION COMPRISING A TENSIONING AGENT AND A HYDROXYALKYL UREA | L'ORÉAL (FR) | 2006-06-01 | — | — | WO | claimed |
| US-20060111490-A1 | Composition comprising a urea compound | L'OREAL (FR) | 2006-05-25 | — | — | US | claimed |
| WO-2006048339-A2 | COSMETIC COMPOSITION COMRISING AN ACTIVE AGENT AND A UREA COMPOUND | L'ORÉAL (FR) | 2006-05-11 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060177393-A1 | Sunscreen compositions comprising lipophilic UV-screening agents and hydroxyalkylurea compounds | CUTA, S100A11, KRT18 | MAPT 2165/4885CA12 4313/4885CA1 4604/4885 |
| US-20060177396-A1 | Sunscreen compositions comprising metal oxide mineral pigments and hydroxyalkylurea compounds | HCN3, KRT18, H1-0 | MAPT 1050/4885CA12 2541/4885CA1 3093/4885 |
| US-12042550-B2 | Leave-on hair treatment compositions | ALG3, DEGS1, DSG1 | MAPT 2274/4885CA12 1054/4885CA1 1819/4885 |
| US-20060177394-A1 | Sunscreen compositions comprising insoluble organic UV-screening agents and hydroxyalkylurea compounds | KRT18, CUTA, H1-0 | MAPT 1111/4885CA12 4372/4885CA1 4629/4885 |
| US-20060177395-A1 | Sunscreen compositions comprising hydrophilic UV-screening agents and hydroxyalkylurea compounds | H1-0, KRT18, CCNE1 | MAPT 1767/4885CA12 4104/4885CA1 4480/4885 |
| US-20240122821-A1 | LEAVE-ON HAIR TREATMENT COMPOSITIONS | ALG3, DEGS1, DSG1 | MAPT 2274/4885CA12 1054/4885CA1 1819/4885 |
| US-20060177397-A1 | Self-tanning product comprising two components and means for artificially coloring the skin | CUTA, TYR, ADH7 | MAPT 4792/4885CA12 3663/4885CA1 4208/4885 |
| US-20060193813-A1 | Nanoemulsion containing a hydroxylated urea compound | LIPA, AUP1, NONO | MAPT 283/4885CA12 3877/4885CA1 4658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.