Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16644420 | 0.76 | DGAT1 (0.46) | DGAT1MAP2K1ERN1CA12CA1 | |
| SCHEMBL7950797 | 0.74 | AKR1B1 (0.43) | DGAT1MAP2K1ERN1CA1CA2 | |
| SCHEMBL9740706 | 0.73 | — | — | |
| SCHEMBL19270495 | 0.72 | POLB (0.41) | DGAT1MAP2K1CA2CA5ACA9 | |
| SCHEMBL4006201 | 0.72 | MYC (0.42) | DGAT1MAP2K1ERN1PARP1KDM4E | |
| SCHEMBL10868192 | 0.71 | AKR1C4 (0.42) | CA12CA1CA2CA3CA4 | |
| SCHEMBL30721742 | 0.71 | DGAT1 (0.44) | DGAT1MAP2K1ERN1CA12CA1 | |
| SCHEMBL28187478 | 0.70 | POLB (0.39) | DGAT1MAP2K1CA1CA2CA4 | |
| SCHEMBL10964657 | 0.70 | ERN1 (0.43) | DGAT1MAP2K1ERN1CA1CA2 | |
| SCHEMBL11781857 | 0.68 | CA12 (0.53) | DGAT1MAP2K1ERN1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0185130-B1 | 5-ALKOXY-2,4,6-TRIODO OR TRIBROMO-ISOPHTHALIC-ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND X-RAY CONTRAST AGENTS CONTAINING THEM | BRACCO INDUSTRIA CHIMICA Società per Azioni (IT) | 1988-03-02 | — | — | EP | claimed |
| EP-0185130-A1 | 5-Alkoxy-2,4,6-triodo or tribromo-isophthalic-acid derivatives, process for their preparation and X-ray contrast agents containing them | BRACCO INDUSTRIA CHIMICA Società per Azioni (IT) | 1986-06-25 | — | — | EP | claimed |
| EP-1186305-A1 | New brominated compounds as contrast media for X-ray mammography | Schering Aktiengesellschaft (DE) | 2002-03-13 | — | — | EP | disclosed |
| EP-0185130-B1 | 5-ALKOXY-2,4,6-TRIODO OR TRIBROMO-ISOPHTHALIC-ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND X-RAY CONTRAST AGENTS CONTAINING THEM | BRACCO INDUSTRIA CHIMICA Società per Azioni (IT) | 1988-03-02 | — | — | EP | disclosed |
| EP-0185130-A1 | 5-Alkoxy-2,4,6-triodo or tribromo-isophthalic-acid derivatives, process for their preparation and X-ray contrast agents containing them | BRACCO INDUSTRIA CHIMICA Società per Azioni (IT) | 1986-06-25 | — | — | EP | disclosed |
| EP-0185130-A1 | 5-Alkoxy-2,4,6-triodo or tribromo-isophthalic-acid derivatives, process for their preparation and X-ray contrast agents containing them | BRACCO INDUSTRIA CHIMICA Società per Azioni (IT) | 1986-06-25 | — | — | EP | disclosed |