Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523679 | 0.84 | MTNR1A (1.00) | MTNR1ANPC1RAB9AHTR1AALDH1A1 | |
| SCHEMBL7561873 | 0.81 | MTNR1A (1.00) | MTNR1ANPC1RAB9AHTR1AADRA1A | |
| SCHEMBL7519527 | 0.80 | MTNR1A (1.00) | MTNR1ANPC1RAB9AHTR1AALDH1A1 | |
| SCHEMBL7518458 | 0.79 | MTNR1A (0.69) | MTNR1ANPC1RAB9AHTR1AALDH1A1 | |
| SCHEMBL7521758 | 0.77 | MTNR1A (1.00) | MTNR1ANPC1RAB9AHTR1AALDH1A1 | |
| SCHEMBL5926589 | 0.76 | MTNR1A (0.69) | MTNR1AHTR1AADRA1ADRD2SLC6A4 | |
| SCHEMBL7527287 | 0.75 | MTNR1A (0.77) | MTNR1ANPC1RAB9AHTR1AADRA1A | |
| SCHEMBL6575956 | 0.74 | MTNR1A (0.58) | MTNR1AHTR1AADRA1ADRD2SLC6A4 | |
| SCHEMBL8114251 | 0.74 | MTNR1A (0.64) | MTNR1AKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6174714 | 0.73 | MTNR1A (0.71) | MTNR1AHTR1AADRA1ADRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873993-B1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-02-20 | — | — | EP | disclosed |
| EP-0873993-A1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-10-28 | — | — | EP | disclosed |