Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.69 |
| ▸ | HTR1A | P08908 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523679 | 0.82 | MTNR1A (1.00) | MTNR1AHTR1ANPC1RAB9AHPGD | |
| SCHEMBL6174872 | 0.79 | HTR1A (0.65) | MTNR1AHTR1ADRD2KDM4ESLC6A4 | |
| SCHEMBL7561873 | 0.79 | MTNR1A (1.00) | MTNR1AHTR1ANPC1RAB9AMTNR1B | |
| SCHEMBL3648434 | 0.79 | CTNNB1 (0.47) | MTNR1ANPC1RAB9AGAAHPGD | |
| SCHEMBL7526209 | 0.79 | MTNR1A (0.72) | MTNR1AHTR1ANPC1RAB9AADRA1A | |
| SCHEMBL7519527 | 0.78 | MTNR1A (1.00) | MTNR1AHTR1ANPC1RAB9AHPGD | |
| SCHEMBL7526194 | 0.78 | MTNR1A (0.68) | MTNR1ARAB9AGAAHPGDMTNR1B | |
| SCHEMBL11204329 | 0.77 | ADRB2 (0.46) | MTNR1AALDH1A1 | |
| SCHEMBL7521758 | 0.75 | MTNR1A (1.00) | MTNR1AHTR1ANPC1RAB9AHPGD | |
| SCHEMBL5926589 | 0.74 | MTNR1A (0.69) | MTNR1AHTR1AMTNR1BADRA1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873993-B1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-02-20 | — | — | EP | disclosed |
| US-5919814-A | Heterocyclic compounds | ADIR ET COMPAGNIE (FR) | 1999-07-06 | — | — | US | disclosed |
| EP-0873993-A1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-10-28 | — | — | EP | disclosed |