Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | WNT3A | P56704 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7519527 | 0.96 | MTNR1A (1.00) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL7521758 | 0.92 | MTNR1A (1.00) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL7561873 | 0.86 | MTNR1A (1.00) | MTNR1AMTNR1BKDM4ENPC1RAB9A | |
| SCHEMBL7526209 | 0.84 | MTNR1A (0.72) | MTNR1AALDH1A1NPC1RAB9AHTR1A | |
| SCHEMBL7527287 | 0.83 | MTNR1A (0.77) | MTNR1AMTNR1BNPC1RAB9ACTNNB1 | |
| SCHEMBL5926589 | 0.82 | MTNR1A (0.69) | MTNR1AMTNR1BCTNNB1WNT3AHTR1A | |
| SCHEMBL7518458 | 0.82 | MTNR1A (0.69) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL7522499 | 0.81 | MTNR1A (0.68) | MTNR1AMTNR1BKDM4EALDH1A1HPGD | |
| SCHEMBL8114251 | 0.79 | MTNR1A (0.64) | MTNR1AALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL6174714 | 0.78 | MTNR1A (0.71) | MTNR1AMTNR1BHTR1ADRD2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873993-B1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-02-20 | — | — | EP | disclosed |
| US-5919814-A | Heterocyclic compounds | ADIR ET COMPAGNIE (FR) | 1999-07-06 | — | — | US | disclosed |
| EP-0873993-A1 | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-10-28 | — | — | EP | disclosed |