SCHEMBL7526386

SCHEMBL7526386

CCCc1ccc(-c2ccc(C(=O)OC(=O)O[C@H](C)CC(CC)CC)cc2-c2ccccc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.40
PTPN1 P18031 1/20 0.37
RARB P10826 2/20 0.36
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
PTAFR P25105 1/20 0.36
KDM1A O60341 1/20 0.35
MAPT P10636 3/20 0.35
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
EGFR P00533 1/20 0.34
SCN1A P35498 1/20 0.34
SCN2A Q99250 1/20 0.34
SCN3A Q9NY46 1/20 0.34
HCRTR1 O43613 1/20 0.34
HCRTR2 O43614 1/20 0.34
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7526394 0.94 PDCD1 (0.38) PTGS2PTPN1RARBTAS1R3TAS1R1
SCHEMBL7517692 0.92 PTGS2 (0.44) PTGS2PDCD1CD274PTAFRMAPT
SCHEMBL7517697 0.92 PTGS2 (0.44) PTGS2PDCD1CD274PTAFRMAPT
SCHEMBL7517699 0.86 PDCD1 (0.46) PTGS2PTPN1PDCD1CD274MAPT
SCHEMBL9850409 0.82 RARB (0.48) RARBPTAFRMAPTALDH1A1
SCHEMBL7520431 0.81 SCN1A (0.34) PTPN1RARBMAPTSCN1ASCN2A
SCHEMBL6564029 0.79 NPC1 (0.41) RARBMAPTCYP4F2CYP4A11HCRTR1
SCHEMBL6563502 0.79 PDCD1 (0.48) PTGS2PDCD1CD274MAPTEGFR
SCHEMBL6563509 0.79 PDCD1 (0.48) PTGS2PDCD1CD274MAPTEGFR
SCHEMBL6562073 0.77 CYP4F2 (0.48) RARBTAS1R3TAS1R1PDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020146517-A1 Optically active compound and liquid crystal composition containing the compound MITSUBISHI GAS CHEMICAL COMPANY, INC. 2002-10-10 US disclosed