Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746416 | 0.93 | PPARG (0.42) | PPARGCES2CES1ADRB1ADRA2A | |
| SCHEMBL7523840 | 0.93 | PPARG (0.42) | PPARGCES2CES1ADRB1ADRA2A | |
| SCHEMBL4290441 | 0.93 | PPARG (0.42) | PPARGCES2CES1ADRB1ADRA2A | |
| SCHEMBL4825249 | 0.93 | PPARG (0.42) | PPARGCES2CES1ADRB1ADRA2A | |
| SCHEMBL8746393 | 0.91 | CES2 (0.42) | PPARGCES2CES1ADRB1ADRA2A | |
| SCHEMBL7786189 | 0.86 | CES2 (0.44) | PPARGCES2CES1ADRB1ADRA2A | |
| SCHEMBL10091381 | 0.81 | CES2 (0.45) | CES2CES1ADRB1ADRA2AADRB3 | |
| SCHEMBL26326732 | 0.80 | PPARG (0.47) | PPARGCES2CES1CSNK1EPPARA | |
| SCHEMBL4910363 | 0.78 | PPARG (0.45) | PPARGCES2CES1CSNK1EPPARA | |
| SCHEMBL30557985 | 0.78 | PPARG (0.45) | PPARGCES2CES1CSNK1EPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214306-A1 | LIQUID CRYSTAL COMPOUNDS | Qinetiq Limited (GB) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001021606-A1 | LIQUID CRYSTAL COMPOUNDS | QINETIQ LIMITED (GB) | 2001-03-29 | — | — | WO | disclosed |