Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30557985 | 0.98 | PPARG (0.45) | PPARGCSNK1EPPARAMEN1ALDH1A1 | |
| SCHEMBL4910363 | 0.98 | PPARG (0.45) | PPARGCSNK1EPPARAMEN1ALDH1A1 | |
| SCHEMBL6630352 | 0.93 | ALDH1A1 (0.42) | PPARGMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL1913425 | 0.87 | CES2 (0.42) | MEN1ALDH1A1LMNAKMT2ANPSR1 | |
| SCHEMBL7523840 | 0.86 | PPARG (0.42) | PPARGCSNK1EPPARAMEN1LMNA | |
| SCHEMBL4290441 | 0.86 | PPARG (0.42) | PPARGCSNK1EPPARAMEN1LMNA | |
| SCHEMBL8746416 | 0.86 | PPARG (0.42) | PPARGCSNK1EPPARAMEN1LMNA | |
| SCHEMBL4825249 | 0.86 | PPARG (0.42) | PPARGCSNK1EPPARAMEN1LMNA | |
| SCHEMBL8746393 | 0.84 | CES2 (0.42) | PPARGCSNK1EPPARAALDH1A1SPHK1 | |
| SCHEMBL24920008 | 0.82 | CSNK1E (0.41) | PPARGCSNK1EMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271988-A1 | METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2023-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271988-A1 | METHOD FOR PRODUCING ORGANOMETALLIC NUCLEOPHILE AND REACTION METHOD USING ORGANOMETALLIC NUCLEOPHILE | HPD, TALDO1, OGG1 | PPARG 3225/4885CSNK1E 4154/4885PPARA 3202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.