SCHEMBL7527136

SCHEMBL7527136

CC1=C(C)C([Si](C)(C)[Ti])c2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.32
ALDH1A1 P00352 1/20 0.32
NPC1 O15118 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6673596 0.84 GPR3 (0.34) GPR3NPC1CASP3RAB9ASMN1; SMN2
SCHEMBL4651299 0.84 GPR3 (0.34) GPR3NPC1CASP3RAB9ASMN1; SMN2
SCHEMBL7946417 0.81 GPR3 (0.36) GPR3NPC1CASP3RAB9ASMN1; SMN2
SCHEMBL23141276 0.74
SCHEMBL29897876 0.74
SCHEMBL7630038 0.74
SCHEMBL5981387 0.72 GPR3 (0.46) GPR3ALDH1A1
Hydrochloric Acid SCHEMBL8022568 0.72 GAA (0.30)
SCHEMBL6056433 0.70
SCHEMBL1941203 0.69 GPR3 (0.38) GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020019490-A1 Polypropylene/ethylene polymer fiber having improved bond performance and composition for making the same THE DOW CHEMICAL COMPANY 2002-02-14 US disclosed