Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7630038 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL995806 | 0.85 | GPR3 (0.34) | GAA | |
| Hydrochloric Acid SCHEMBL6858048 | 0.82 | GPR3 (0.34) | GAA | |
| Hydrochloric Acid SCHEMBL6862745 | 0.82 | GPR3 (0.34) | GAA | |
| SCHEMBL7510367 | 0.82 | GPR3 (0.36) | — | |
| SCHEMBL6903006 | 0.81 | APAF1 (0.36) | GAA | |
| SCHEMBL540904 | 0.80 | GPR3 (0.35) | — | |
| SCHEMBL28790426 | 0.78 | GPR3 (0.33) | — | |
| SCHEMBL29171300 | 0.76 | GPR3 (0.32) | — | |
| SCHEMBL4651299 | 0.75 | GPR3 (0.34) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6015868-A | CATALYSIS OF HIGH TEMPERATURE, SOLUTION POLYMERIZATION WHICH YIELDS HIGH MOLECULAR WEIGHT OLEFIN POLYMERS, BY USING COORDINATION CATALYST MIXED WITH AN ACTIVATING COCATALYST, EFFICIENCY | THE DOW CHEMICAL COMPANY (US) | 2000-01-18 | — | — | US | disclosed |