Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.88 |
| ▸ | HTR2C | P28335 | 2/20 | 0.88 |
| ▸ | DRD2 | P14416 | 2/20 | 0.88 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.88 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.88 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.88 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.88 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.88 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.88 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.88 |
| ▸ | HTR2A | P28223 | 1/20 | 0.88 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.88 |
| ▸ | HRH1 | P35367 | 1/20 | 0.88 |
| ▸ | HTR2B | P41595 | 1/20 | 0.88 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.88 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.88 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.88 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.88 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxypertine SCHEMBL31153315 | 0.94 | DRD2 (1.00) | HTR1AHTR2CDRD2NR1I2ADRB1 | |
| Oxypertine SCHEMBL1515 | 0.94 | DRD2 (1.00) | HTR1AHTR2CDRD2NR1I2ADRB1 | |
| Oxypertine SCHEMBL2463001 | 0.94 | DRD2 (1.00) | HTR1AHTR2CDRD2NR1I2ADRB1 | |
| Oxypertine SCHEMBL20270862 | 0.93 | DRD2 (0.98) | HTR1AHTR2CDRD2NR1I2ADRB1 | |
| Oxypertine SCHEMBL5069690 | 0.93 | DRD2 (0.98) | HTR1AHTR2CDRD2NR1I2ADRB1 | |
| Oxypertine SCHEMBL3478579 | 0.93 | DRD2 (0.98) | HTR1AHTR2CDRD2NR1I2ADRB1 | |
| Oxypertine SCHEMBL3440995 | 0.93 | DRD2 (0.98) | HTR1AHTR2CDRD2NR1I2ADRB1 | |
| Oxypertine SCHEMBL21268763 | 0.91 | HTR1A (0.94) | HTR1AHTR2CDRD2NR1I2ADRB1 | |
| Oxypertine SCHEMBL2837214 | 0.91 | DRD2 (0.94) | HTR1AHTR2CDRD2NR1I2ADRB1 | |
| SCHEMBL2615395 | 0.86 | DRD2 (0.84) | HTR1AHTR2CDRD2NR1I2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187825-A1 | THIOPHENE INTEGRIN INHIBITORS | Shire Biochem Inc. (CA) | 2002-03-20 | — | — | EP | disclosed |