Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.98 |
| ▸ | HTR1A | P08908 | 2/20 | 0.98 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.98 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.98 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.98 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.98 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.98 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.98 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.98 |
| ▸ | HTR2A | P28223 | 1/20 | 0.98 |
| ▸ | HTR2C | P28335 | 1/20 | 0.98 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.98 |
| ▸ | HRH1 | P35367 | 1/20 | 0.98 |
| ▸ | HTR2B | P41595 | 1/20 | 0.98 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.98 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.98 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.98 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.98 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxypertine SCHEMBL1515 | 0.99 | DRD2 (1.00) | DRD2HTR1ANR1I2ADRB1ADRA2A | |
| Oxypertine SCHEMBL31153315 | 0.99 | DRD2 (1.00) | DRD2HTR1ANR1I2ADRB1ADRA2A | |
| Oxypertine SCHEMBL2463001 | 0.99 | DRD2 (1.00) | DRD2HTR1ANR1I2ADRB1ADRA2A | |
| Oxypertine SCHEMBL3478579 | 0.98 | DRD2 (0.98) | DRD2HTR1ANR1I2ADRB1ADRA2A | |
| Oxypertine SCHEMBL5069690 | 0.98 | DRD2 (0.98) | DRD2HTR1ANR1I2ADRB1ADRA2A | |
| Oxypertine SCHEMBL20270862 | 0.98 | DRD2 (0.98) | DRD2HTR1ANR1I2ADRB1ADRA2A | |
| Oxypertine SCHEMBL21268763 | 0.96 | HTR1A (0.94) | DRD2HTR1ANR1I2ADRB1ADRA2A | |
| Oxypertine SCHEMBL2837214 | 0.96 | DRD2 (0.94) | DRD2HTR1ANR1I2ADRB1ADRA2A | |
| Oxypertine SCHEMBL7527152 | 0.93 | HTR1A (0.88) | DRD2HTR1ANR1I2ADRB1ADRA2A | |
| SCHEMBL2615395 | 0.91 | DRD2 (0.84) | DRD2HTR1ANR1I2ADRB1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2826371-B1 | Methods and compositions for inhibiting integrins using tellurium-containing compounds | FERAMDA LTD (IL) | 2019-01-02 | — | — | EP | disclosed |
| EP-2826371-A2 | Methods and compositions for inhibiting integrins using tellurium-containing compounds | Biomas Ltd. (IL) | 2015-01-21 | — | — | EP | disclosed |
| US-20140194496-A1 | METHODS AND COMPOSITIONS FOR INHIBITING INTEGRINS USING TELLURIUM-CONTAINING COMPOUNDS | BIOMAS LTD. (IL) | 2014-07-10 | — | — | US | disclosed |
| US-20100297256-A1 | METHODS AND COMPOSITIONS FOR INHIBITING INTEGRINS USING TELLURIUM-CONTAINING COMPOUNDS | BIOMAS LTD. (IL) | 2010-11-25 | — | — | US | disclosed |
| EP-2222167-A2 | METHODS AND COMPOSITIONS FOR INHIBITING INTEGRINS USING TELLURIUM-CONTAINING COMPOUNDS | Biomas Ltd. (IL) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009066300-A2 | METHODS AND COMPOSITIONS FOR INHIBITING INTEGRINS USING TELLURIUM-CONTAINING COMPOUNDS | BIOMAS LTD. (IL) | 2009-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140194496-A1 | METHODS AND COMPOSITIONS FOR INHIBITING INTEGRINS USING TELLURIUM-CONTAINING COMPOUNDS | ITGB5, ITGB2, ITGB3 | DRD2 4773/4885HTR1A 4669/4885NR1I2 2780/4885 |
| US-20100297256-A1 | METHODS AND COMPOSITIONS FOR INHIBITING INTEGRINS USING TELLURIUM-CONTAINING COMPOUNDS | ITGB5, ITGB2, ITGB1 | DRD2 4732/4885HTR1A 4682/4885NR1I2 2869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.