Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7529687 | 0.88 | ALDH1A1 (0.42) | CES2CES1L3MBTL1ALDH1A1SNCA | |
| SCHEMBL7525593 | 0.88 | CES2 (0.41) | CES2CES1L3MBTL1ALDH1A1SNCA | |
| SCHEMBL7529260 | 0.88 | CES2 (0.41) | CES2CES1L3MBTL1ALDH1A1SNCA | |
| SCHEMBL7532764 | 0.87 | ALDH1A1 (0.44) | CES2CES1L3MBTL1ALDH1A1SNCA | |
| SCHEMBL7528950 | 0.87 | L3MBTL1 (0.42) | CES2CES1L3MBTL1ALDH1A1SNCA | |
| SCHEMBL6415999 | 0.86 | CES2 (0.45) | CES2CES1L3MBTL1ALDH1A1SNCA | |
| SCHEMBL7525508 | 0.86 | CES2 (0.40) | CES2CES1L3MBTL1ALDH1A1SNCA | |
| SCHEMBL7525193 | 0.86 | CES2 (0.40) | CES2CES1L3MBTL1ALDH1A1SNCA | |
| SCHEMBL7523818 | 0.85 | ALDH1A1 (0.42) | CES2CES1L3MBTL1ALDH1A1SNCA | |
| SCHEMBL7523810 | 0.85 | ALDH1A1 (0.42) | CES2CES1L3MBTL1ALDH1A1SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1184367-A1 | AMIDE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-03-06 | — | — | EP | disclosed |