Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14112017 | 0.84 | KMT2A (0.65) | MAPTKMT2AHPGDSMN1; SMN2GAA | |
| SCHEMBL9124359 | 0.83 | KMT2A (0.63) | MAPTKMT2AHPGDSMN1; SMN2GAA | |
| SCHEMBL2719871 | 0.82 | KMT2A (0.67) | MAPTKMT2AHPGDSMN1; SMN2GAA | |
| SCHEMBL14112016 | 0.82 | EPHX2 (0.67) | MAPTKMT2AHPGDSMN1; SMN2GAA | |
| SCHEMBL11613615 | 0.81 | KMT2A (0.61) | MAPTKMT2AHPGDSMN1; SMN2GAA | |
| SCHEMBL9125404 | 0.80 | HPGD (0.59) | MAPTKMT2AHPGDSMN1; SMN2GAA | |
| SCHEMBL21276486 | 0.80 | HPGD (0.53) | MAPTKMT2AHPGDSMN1; SMN2GAA | |
| SCHEMBL9360937 | 0.80 | KDM4E (0.61) | MAPTKMT2AHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL9080 | 0.80 | GAA (0.66) | KMT2AHPGDSMN1; SMN2GAAPOLB | |
| SCHEMBL10433480 | 0.79 | KMT2A (0.65) | MAPTKMT2AHPGDSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263506-B1 | ANTICONVULSANT COMPOSITION CONTAINING AMINO ACID DERIVATIVE AND USE OF SAID AMINO ACID DERIVATIVE | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-08-04 | — | — | EP | claimed |
| EP-0263506-A2 | Anticonvulsant composition containing amino acid derivative and use of said amino acid derivative | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1988-04-13 | — | — | EP | claimed |
| EP-0400440-B1 | Amino acid derivative anticonvulsant | RES CORP TECHNOLOGIES INC (US) | 2002-03-13 | — | — | EP | disclosed |
| EP-0263506-B1 | ANTICONVULSANT COMPOSITION CONTAINING AMINO ACID DERIVATIVE AND USE OF SAID AMINO ACID DERIVATIVE | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-08-04 | — | — | EP | disclosed |
| EP-0400440-A1 | Amino acid derivative anticonvulsant | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1990-12-05 | — | — | EP | disclosed |
| EP-0263506-A2 | Anticonvulsant composition containing amino acid derivative and use of said amino acid derivative | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1988-04-13 | — | — | EP | disclosed |