Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360784 | 0.85 | NPSR1 (0.51) | HSD17B10HTTHPGDNPSR1NPC1 | |
| SCHEMBL14055032 | 0.83 | HTT (0.54) | HTTHPGDNPC1HIF1AMEN1 | |
| SCHEMBL7527675 | 0.80 | MAPT (0.64) | POLBHSD17B10HTTHPGDMAPT | |
| SCHEMBL7539272 | 0.79 | HTT (0.54) | KDM4EPOLBHTTHPGDNPC1 | |
| Ether SCHEMBL10909199 | 0.77 | KDM4E (0.53) | KDM4EPOLBHSD17B10HTTHPGD | |
| SCHEMBL27617171 | 0.77 | HTT (0.51) | HTTHPGDNPC1HIF1AMEN1 | |
| SCHEMBL7541780 | 0.77 | HTT (0.51) | KDM4EPOLBHTTHPGDMAPT | |
| SCHEMBL9848860 | 0.76 | HTT (0.57) | KDM4EHTTHPGDNPSR1HIF1A | |
| SCHEMBL12164265 | 0.76 | KDM4E (0.55) | KDM4EPOLBHTTNPC1HIF1A | |
| SCHEMBL9361352 | 0.76 | KDM4E (1.00) | KDM4EPOLBHSD17B10HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412529-B1 | Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same | NIPPON CHEMIPHAR CO (JP) | 1994-03-09 | — | — | EP | disclosed |
| US-5091403-A | SULFINYL IMIDAZOLE DERIVATIVES AND ANTIULCER AGENTS CONTAINING THE SAME | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |
| EP-0412529-A1 | Imidazole derivatives, process for the preparation of the same and antiulcer agents containing the same | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-02-13 | — | — | EP | disclosed |