Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125404 | 0.85 | HPGD (0.59) | KMT2AHPGDGAATSHRRECQL | |
| SCHEMBL13865100 | 0.85 | KMT2A (0.52) | KMT2AHPGDGAATSHRRECQL | |
| SCHEMBL26581051 | 0.84 | TSHR (0.63) | KMT2AHPGDGAATSHRRECQL | |
| SCHEMBL26581062 | 0.84 | TSHR (0.63) | KMT2AHPGDGAATSHRRECQL | |
| SCHEMBL14112017 | 0.83 | KMT2A (0.65) | KMT2AHPGDGAATSHRSMN1; SMN2 | |
| SCHEMBL9124359 | 0.81 | KMT2A (0.63) | KMT2AHPGDGAATSHRRECQL | |
| SCHEMBL7527675 | 0.81 | MAPT (0.64) | KMT2AHPGDGAASMN1; SMN2RAB9A | |
| SCHEMBL14112016 | 0.80 | EPHX2 (0.67) | KMT2AHPGDGAATSHRRECQL | |
| SCHEMBL16326841 | 0.80 | KMT2A (0.54) | KMT2AHPGDGAATSHRRECQL | |
| SCHEMBL13373646 | 0.78 | L3MBTL1 (0.52) | KMT2AHPGDGAASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107235852-B | A kind of method of synthesizing amide | 南京理工大学 | 2019-05-31 | — | — | CN | disclosed |
| CN-107235852-A | A kind of method of synthesizing amide | 南京理工大学 | 2017-10-10 | — | — | CN | disclosed |
| US-4130711-A | DEHYDROGENATION OF A N-HYDROXYALKYL N-AMIDOALKYL AMINE, REDUCED COPPER CATALYST | THE DOW CHEMICAL COMPANY (US) | 1978-12-19 | — | — | US | disclosed |
| US-4082748-A | CATALYTIC DEHYDROCYCLIZATION | THE DOW CHEMICAL COMPANY (US) | 1978-04-04 | — | — | US | disclosed |