Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL752785

S.c1csc(-c2ccccc2-c2cccs2)c1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.53
KDM4E B2RXH2 8/20 0.46
ALDH1A1 P00352 7/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
HPGD P15428 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
MAPT P10636 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
RAB9A P51151 7/20 0.46
NPC1 O15118 6/20 0.46
ATM Q13315 1/20 0.46
LTK P29376 1/20 0.46
CDK5 Q00535 1/20 0.46
MST1R Q04912 1/20 0.46
DYRK1A Q13627 1/20 0.46
CLK4 Q9HAZ1 1/20 0.46
TDO2 P48775 1/20 0.45
SMN1; SMN2 Q16637 4/20 0.44
MAOB P27338 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL995326 0.97 LTA4H (0.55) LTA4HKDM4EALDH1A1L3MBTL1HPGD
Hydrogen Sulfide SCHEMBL27605763 0.89 LTA4H (0.46) LTA4HKDM4EALDH1A1L3MBTL1HPGD
SCHEMBL14190039 0.87 LTA4H (0.48) LTA4HKDM4EALDH1A1L3MBTL1HPGD
Hydrogen Sulfide SCHEMBL27800916 0.87 LTA4H (0.44) LTA4HKDM4EALDH1A1L3MBTL1HPGD
SCHEMBL3084911 0.85 LTA4H (0.47) LTA4HKDM4EALDH1A1L3MBTL1HPGD
Hydrogen Sulfide SCHEMBL28276156 0.84 RAB9A (0.59) LTA4HKDM4EALDH1A1L3MBTL1HPGD
Hydrogen Sulfide SCHEMBL22588115 0.82 L3MBTL1 (0.55) LTA4HKDM4EALDH1A1L3MBTL1HPGD
SCHEMBL27489324 0.82 MAPT (0.53) LTA4HKDM4EALDH1A1L3MBTL1HPGD
SCHEMBL7212806 0.81 KDM4E (0.50) LTA4HKDM4EALDH1A1L3MBTL1HPGD
SCHEMBL29945128 0.81 LTA4H (0.47) LTA4HKDM4EALDH1A1L3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8349916-B2 Actinic energy radiation curable ink-jet ink, ink-jet recording method, and printed matter KONICA MINOLTA IJ TECHNOLOGIES, INC. (JP) 2013-01-08 US disclosed
EP-2228415-B1 Actinic energy radiation curable ink-jet ink, ink-jet recoring method, and printed matter KONICA MINOLTA IJ TECHNOLOGIES (JP) 2012-03-21 EP disclosed
US-20100255211-A1 ACTINIC ENERGY RADIATION CURABLE INK-JET INK AND INK-JET IMAGE FORMING METHOD KONICA MINOLTA IJ TECHNOLOGIES, INC. (JP) 2010-10-07 US disclosed
EP-2236568-A1 Actinic energy radiation curable ink-jet ink and ink-jet image forming method Konica Minolta IJ Technologies, Inc. (JP) 2010-10-06 EP disclosed
US-20100233446-A1 ACTINIC ENERGY RADIATION CURABLE INK-JET INK, INK-JET RECORDING METHOD, AND PRINTED MATTER KONICA MINOLTA IJ TECHNOLOGIES, INC. (JP) 2010-09-16 US disclosed
EP-2228415-A1 Acting energy radiation curable ink-jet ink, ink-jet recoring method, and printed matter Konica Minolta IJ Technologies, Inc. (JP) 2010-09-15 EP disclosed