Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.42 |
| ▸ | PDE7B | Q9NP56 | 4/20 | 0.42 |
| ▸ | CCR2 | P41597 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL752794 | 1.00 | KIF18A (0.59) | KIF18AMAPK1TSHRVCAM1FLT1 | |
| SCHEMBL1052777 | 0.81 | KIF18A (0.64) | KIF18AMAPK1TSHRVCAM1FLT1 | |
| SCHEMBL30821752 | 0.81 | KIF18A (0.64) | KIF18AMAPK1TSHRVCAM1FLT1 | |
| SCHEMBL751494 | 0.80 | TSHR (0.55) | TSHRVCAM1ALDH1A1 | |
| SCHEMBL751493 | 0.80 | TSHR (0.55) | TSHRVCAM1ALDH1A1 | |
| SCHEMBL9012097 | 0.79 | KIF18A (0.62) | KIF18AMAPK1TSHRVCAM1FLT1 | |
| SCHEMBL27334707 | 0.79 | KIF18A (0.62) | KIF18AMAPK1TSHRVCAM1FLT1 | |
| SCHEMBL7813933 | 0.79 | KIF18A (0.62) | KIF18AMAPK1TSHRVCAM1FLT1 | |
| SCHEMBL32679728 | 0.79 | KIF18A (0.62) | KIF18AMAPK1TSHRVCAM1FLT1 | |
| Hydrochloric Acid SCHEMBL28104854 | 0.78 | KIF18A (0.60) | KIF18AMAPK1TSHRVCAM1FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2213166-A1 | Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone | THOR GmbH (DE) | 2010-08-04 | — | — | EP | claimed |
| EP-2213166-B1 | Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone | THOR GMBH (DE) | 2012-03-21 | — | — | EP | disclosed |
| EP-2216372-A1 | Compounds for preventing Ghost odour | THOR GmbH (DE) | 2010-08-11 | — | — | EP | disclosed |
| EP-2213166-A1 | Biocidal compounds containing 2-methylisothiazolin-3-one and a haloalkylsulfone | THOR GmbH (DE) | 2010-08-04 | — | — | EP | disclosed |