Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 18/20 | 0.49 |
| ▸ | DRD1 | P21728 | 18/20 | 0.49 |
| ▸ | DRD5 | P21918 | 16/20 | 0.49 |
| ▸ | DRD4 | P21917 | 10/20 | 0.49 |
| ▸ | DRD3 | P35462 | 13/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7139434 | 0.91 | DRD2 (0.47) | DRD2DRD1DRD5DRD4DRD3 | |
| SCHEMBL5658358 | 0.80 | DRD2 (0.44) | DRD2DRD1DRD5DRD4DRD3 | |
| SCHEMBL1276263 | 0.76 | DRD2 (0.56) | DRD2DRD1DRD5DRD4DRD3 | |
| SCHEMBL250734 | 0.73 | CYP2A6 (0.65) | DRD2DRD1DRD5DRD4DRD3 | |
| SCHEMBL12191968 | 0.73 | DRD1 (0.49) | DRD2DRD1DRD5DRD4DRD3 | |
| SCHEMBL2771201 | 0.73 | CYP2A6 (0.48) | DRD2DRD1DRD5DRD4DRD3 | |
| SCHEMBL8893845 | 0.70 | CYP2A6 (0.38) | DRD2DRD1DRD5DRD4DRD3 | |
| SCHEMBL6903685 | 0.69 | DRD1 (0.76) | DRD2DRD1DRD5DRD4DRD3 | |
| SCHEMBL6901150 | 0.69 | DRD1 (0.73) | DRD2DRD1DRD5DRD4DRD3 | |
| SCHEMBL1445130 | 0.69 | CYP2A6 (0.43) | DRD2DRD1DRD5DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189887-A2 | PROCESS FOR PREPARING 10,11-METHANOBENZOSUBERANE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-03-27 | — | — | EP | disclosed |
| WO-2000075121-A2 | PROCESS FOR PREPARING 10,11-METHANOBENZOSUBERANE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2000-12-14 | — | — | WO | disclosed |