SCHEMBL1276263

SCHEMBL1276263

Oc1cccc2c1CCc1ccccc1C2

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 10/20 0.56
DRD1 P21728 9/20 0.56
DRD3 P35462 8/20 0.56
DRD5 P21918 8/20 0.56
BCL2L1 Q07817 1/20 0.55
BAD Q92934 1/20 0.55
DRD4 P21917 4/20 0.45
MEN1 O00255 1/20 0.44
USP2 O75604 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HPN P05981 1/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX5 P09917 1/20 0.44
MAPT P10636 1/20 0.44
THRB P10828 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
PTGS1 P23219 1/20 0.44
PDE4A P27815 1/20 0.44
KDR P35968 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7918691 0.85 DRD2 (0.61) DRD2DRD1DRD3DRD5BCL2L1
SCHEMBL31634362 0.85 DRD2 (0.61) DRD2DRD1DRD3DRD5BCL2L1
SCHEMBL29414699 0.84
SCHEMBL150017 0.84
SCHEMBL6905223 0.80 BCL2L1 (0.54) DRD2DRD1DRD3DRD5BCL2L1
Formaldehyde SCHEMBL17491106 0.78 BCL2L1 (0.65) DRD2DRD1DRD3DRD5BCL2L1
SCHEMBL31379414 0.78 CYP2A6 (0.46) DRD2DRD1DRD3DRD5DRD4
SCHEMBL266203 0.78 BCL2L1 (0.53) DRD2DRD1DRD3DRD5BCL2L1
SCHEMBL250734 0.76 CYP2A6 (0.65) DRD2DRD1DRD3DRD5DRD4
SCHEMBL7527997 0.76 DRD2 (0.49) DRD2DRD1DRD3DRD5DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118791533-A Compound and preparation method thereof, and preparation method of polyolefin elastomer 中国科学院长春应用化学研究所 2024-10-18 CN claimed
CN-111909196-A IVB group-containing bimetallic complex catalyst and preparation method and application thereof 万华化学集团股份有限公司 2020-11-10 CN claimed
WO-2012104262-A1 PHOTORESPONSIVE MICROCAPSULES AND COMPOSITIONS CONTAINING SAME UNIVERSIDAD DE SEVILLA (ES) 2012-08-09 WO claimed
EP-2467122-A2 PHOTORESPONSIVE SUNSCREEN COMPOSITION Blueshift Pharma GmbH (CH) 2012-06-27 EP claimed
US-20120148647-A1 Photoresponsive Sunscreen Composition BLUESHIFT PHARMA GMBH (CH) 2012-06-14 US claimed
WO-2011020928-A2 PHOTORESPONSIVE SUNSCREEN COMPOSITION BLUESHIFT PHARMA GMBH (CH) 2011-02-24 WO claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
US-6797745-B1 Hot melt inks containing styrene or terpene polymers XEROX CORPORATION 2004-09-28 US claimed
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US claimed
EP-0677076-B1 DIARYL CARBINOL METATHESIS CATALYSTS SHELL OIL CO (US) 1997-04-16 EP claimed
EP-0677076-A1 DIARYL CARBINOL METATHESIS CATALYSTS. SHELL OIL CO (US) 1995-10-18 EP claimed
WO-1994015989-A1 DIARYL CARBINOL METATHESIS CATALYSTS SHELL OIL COMPANY (US) 1994-07-21 WO claimed
US-5276118-A Metal complex SHELL OIL COMPANY (US) 1994-01-04 US claimed
EP-3400233-B1 PHARMACEUTICAL COMPOSITIONS AND METHODS POP TEST ONCOLOGY LLC (US) 2025-10-22 EP disclosed
US-12263178-B2 Pharmaceutical compositions and methods POP TEST ONCOLOGY LLC (US) 2025-04-01 US disclosed
US-20240358718-A1 CONCOMITANT ADMINISTRATION OF GLUCOCORTICOID RECEPTOR MODULATORS AND CYP3A INHIBITORS CORCEPT THERAPEUTICS, INC. (US) 2024-10-31 US disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120148647-A1 Photoresponsive Sunscreen Composition SUN2, MC1R, MITF DRD2 3593/4885DRD1 3004/4885DRD3 3624/4885
US-20240358718-A1 CONCOMITANT ADMINISTRATION OF GLUCOCORTICOID RECEPTOR MODULATORS AND CYP3A INHIBITORS NR3C1, NR3C2, CYP3A5 DRD2 2195/4885DRD1 1883/4885DRD3 1639/4885
US-12263178-B2 Pharmaceutical compositions and methods NR3C2, NR3C1, MC2R DRD2 3609/4885DRD1 4220/4885DRD3 3218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.