Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 14/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 10/20 | 0.61 |
| ▸ | HTR2A | P28223 | 7/20 | 0.61 |
| ▸ | HTR1A | P08908 | 7/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.61 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.61 |
| ▸ | HRH1 | P35367 | 2/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 6/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.60 |
| ▸ | DRD2 | P14416 | 14/20 | 0.59 |
| ▸ | DRD4 | P21917 | 4/20 | 0.59 |
| ▸ | DRD1 | P21728 | 2/20 | 0.58 |
| ▸ | HTR2B | P41595 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7531187 | 0.99 | DRD3 (0.60) | DRD3ADRA1AHTR2AHTR1AADRA2A | |
| SCHEMBL7342776 | 0.89 | DRD2 (0.68) | DRD3ADRA1AHTR2AHTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL7351318 | 0.88 | DRD2 (0.67) | DRD3ADRA1AHTR2AHTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL7350351 | 0.85 | DRD2 (0.76) | DRD3ADRA1AHTR2AHTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL7424220 | 0.84 | DRD2 (0.57) | DRD3ADRA1AHTR2AHTR1AADRA2A | |
| SCHEMBL7526939 | 0.83 | DRD3 (0.77) | DRD3ADRA1AHTR2AHTR1AADRA1D | |
| SCHEMBL7528464 | 0.81 | DRD2 (0.79) | DRD3ADRA1AHTR2AHTR1AADRA2A | |
| SCHEMBL7530035 | 0.81 | DRD3 (0.79) | DRD3ADRA1AHTR2AHTR1AADRA1D | |
| SCHEMBL7529338 | 0.81 | DRD2 (0.79) | DRD3ADRA1AHTR2AHTR1AHTR2C | |
| SCHEMBL3265484 | 0.80 | HTR2A (0.60) | DRD3HTR2AHTR1AHTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0898567-B1 | N-AMINOALKYL-1-BIPHENYLENYL-2-CARBOXAMIDES; DOPAMINE RECEPTOR SUBTYPE SPECIFIC LIGANDS | NEUROGEN CORP (US) | 2002-04-03 | — | — | EP | claimed |