Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.60 |
| ▸ | HTR2C | P28335 | 3/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3268873 | 0.89 | DRD2 (0.55) | HTR2AHTR2CHTR1ADRD2DRD3 | |
| Hydrochloric Acid SCHEMBL7531187 | 0.81 | DRD3 (0.60) | HTR2AHTR2CSLC6A4HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL7351318 | 0.81 | DRD2 (0.67) | HTR2AHTR2CSLC6A4HTR1ADRD2 | |
| SCHEMBL3265653 | 0.81 | DRD3 (0.67) | HTR2AHTR2CSLC6A4HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL10562530 | 0.80 | HTR1A (0.64) | HTR1ADRD2DRD3 | |
| SCHEMBL7342776 | 0.80 | DRD2 (0.68) | HTR2AHTR2CSLC6A4HTR1ADRD2 | |
| SCHEMBL7528070 | 0.80 | DRD3 (0.61) | HTR2AHTR2CSLC6A4HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL7424220 | 0.78 | DRD2 (0.57) | HTR2AHTR2CSLC6A4HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL2215609 | 0.76 | HTR2A (0.82) | HTR2AHTR2CSLC6A4HTR1ADRD2 | |
| SCHEMBL2216114 | 0.76 | HTR2A (0.76) | HTR2AHTR2CSLC6A4HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010038948-A2 | ARYLPIPERAZINE-CONTAINING PYRROLE 3-CARBOXAMIDE DERIVATIVES FOR TREATING DEPRESSIVE DISORDERS | GREEN CROSS CORPORATION (KR) | 2010-04-08 | — | — | WO | disclosed |