SCHEMBL7528131

SCHEMBL7528131

Cc1ccc(C2CC(=O)OC2=O)c2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.44
HPGD P15428 5/20 0.44
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
THRB P10828 2/20 0.44
USP2 O75604 1/20 0.44
ALDH1A1 P00352 6/20 0.43
ALDH2 P05091 1/20 0.43
CYP1A2 P05177 1/20 0.41
TP53 P04637 2/20 0.39
PLA2G6 O60733 3/20 0.38
MAPK1 P28482 2/20 0.38
FAAH O00519 1/20 0.38
NPC1 O15118 1/20 0.38
GMNN O75496 1/20 0.38
LMNA P02545 1/20 0.38
MTOR P42345 1/20 0.38
RAB9A P51151 1/20 0.38
BLM P54132 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7531010 0.82 ALDH1A1 (0.39) MAPTHPGDMEN1KMT2ATHRB
SCHEMBL7533164 0.81 PLA2G6 (0.56) MAPTHPGDMEN1KMT2ATHRB
SCHEMBL10783321 0.78 MAPT (0.49) MAPTHPGDMEN1KMT2ATHRB
SCHEMBL12664899 0.77 CTRC (0.44) MAPTHPGDMEN1KMT2ATHRB
SCHEMBL8993620 0.75 SIRT2 (0.47) MAPTHPGDMEN1KMT2ATHRB
SCHEMBL30772490 0.73 ALDH1A1 (0.42) MAPTHPGDMEN1KMT2ATHRB
SCHEMBL7530180 0.72 ALDH1A1 (0.35) MAPTHPGDMEN1KMT2ATHRB
SCHEMBL31088320 0.72 ALDH1A1 (0.35) MAPTHPGDMEN1KMT2ATHRB
SCHEMBL7527580 0.71 ALDH1A1 (0.35) MAPTHPGDMEN1KMT2ATHRB
SCHEMBL31121816 0.70 CTRC (0.46) MAPTHPGDMEN1KMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0725302-B1 A process of producing a polyimide block copolymer JAPAN SYNTHETIC RUBBER CO LTD (JP) 2002-04-03 EP disclosed
EP-0725302-A2 A process of producing a polyimide block copolymer JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-08-07 EP disclosed