Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137655 | 0.81 | TSHR (0.44) | TSHRMAPTHSD17B10KDM4EMEN1 | |
| SCHEMBL7292120 | 0.80 | SLC6A4 (0.43) | TSHRHSD17B10KDM4EMEN1ALDH1A1 | |
| SCHEMBL535892 | 0.79 | GABRA1 (0.45) | MAPTALDH1A1CYP2D6L3MBTL1GABRA1 | |
| SCHEMBL7768256 | 0.79 | TSHR (0.57) | TSHRMAPTHSD17B10KDM4EMEN1 | |
| SCHEMBL31153347 | 0.79 | TSHR (0.57) | TSHRMAPTHSD17B10KDM4EMEN1 | |
| SCHEMBL13469121 | 0.77 | TSHR (0.52) | TSHRMAPTHSD17B10KDM4EMEN1 | |
| SCHEMBL910448 | 0.74 | DAO (0.38) | MAPTHSD17B10KDM4ECYP1A2CYP2D6 | |
| SCHEMBL3021179 | 0.73 | TRPA1 (0.35) | TSHRALDH1A1CYP1A2GABRA1GABRB2 | |
| SCHEMBL12677859 | 0.71 | MAPT (0.70) | TSHRMAPTHSD17B10KDM4EMEN1 | |
| SCHEMBL26686946 | 0.71 | TSHR (0.50) | TSHRMAPTHSD17B10KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187847-A1 | STREPTOGRAMIN DERIVATIVES, PREPARATION AND COMPOSITIONS CONTAINING THEM | Aventis Pharma S.A. (FR) | 2002-03-20 | — | — | EP | disclosed |
| WO-2001002427-A1 | STREPTOGRAMIN DERIVATIVES, PREPARATION AND COMPOSITIONS CONTAINING THEM | AVENTIS PHARMA S.A. (FR) | 2001-01-11 | — | — | WO | disclosed |