Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | CASP7 | P55210 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1456243 | 0.81 | CES2 (0.42) | POLBALDH1A1MAPTMEN1HPGD | |
| SCHEMBL19695344 | 0.80 | HDAC1 (0.34) | POLBTSHRCES2CES1NFKB1 | |
| SCHEMBL28004163 | 0.80 | HTT (0.39) | KDM4EALDH1A1HPGDHSD17B10CES2 | |
| SCHEMBL28939091 | 0.80 | CES2 (0.32) | POLBCES2CES1 | |
| SCHEMBL11007577 | 0.80 | HTT (0.39) | KDM4EALDH1A1HPGDHSD17B10CES2 | |
| SCHEMBL10804236 | 0.75 | CES2 (0.42) | POLBALDH1A1MAPTMEN1HPGD | |
| SCHEMBL28938074 | 0.73 | CES2 (0.40) | POLBALDH1A1MAPTMEN1HPGD | |
| SCHEMBL812433 | 0.72 | POLB (0.41) | POLBALDH1A1MAPTTSHRKMT2A | |
| SCHEMBL10589653 | 0.72 | POLB (0.33) | POLBKDM4EALDH1A1MAPTCASP1 | |
| SCHEMBL8918066 | 0.72 | HTT (0.42) | POLBKDM4EALDH1A1HSD17B10CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6437168-B1 | FLUORINATION; EFFICIENT EXTRACTION | NIPPON SHOKUBAI CO., LTD. (JP) | 2002-08-20 | — | — | US | disclosed |
| US-20020035301-A1 | Method for production of aromatic fluorine compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2002-03-21 | — | — | US | disclosed |
| EP-0335015-A1 | Self-extinguishing polymeric sheet and large transparent surfaces obtained by means of the combination of a plurality of said sheets | LA/ES LAMINATI ESTRUSI TERMOPLASTICI S.P.A. (IT) | 1989-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035301-A1 | Method for production of aromatic fluorine compound | AFF4, AFF2, AFF1 | POLB 1276/4885SCN10A 3874/4885SCN1A 4144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.