Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263673 | 0.85 | FPR2 (0.47) | ADORA3F2DEGS1NPC1RAB9A | |
| SCHEMBL452423 | 0.85 | KMT2A (0.54) | ADORA3NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL7635962 | 0.84 | DEGS1 (0.48) | DEGS1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL3136443 | 0.82 | ABL1 (0.53) | NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL6046930 | 0.78 | MAPT (0.42) | ADORA3F2DEGS1NPC1RAB9A | |
| SCHEMBL454099 | 0.75 | MAPT (0.50) | F2NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL22672647 | 0.75 | MEN1 (0.54) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL8299962 | 0.74 | MEN1 (0.45) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL27041152 | 0.74 | ADORA3 (0.45) | ADORA3F2NPC1RAB9ARXFP1 | |
| SCHEMBL27041189 | 0.74 | ADORA3 (0.45) | ADORA3F2NPC1RAB9ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465650-B1 | INTERMEDIATE STEPS IN PREPARING PEPTIDE NUCLEIC ACIDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-10-15 | — | — | US | disclosed |
| EP-0761681-B1 | Process for the preparation of substituted derivatives of N-ethylglycine | HOECHST AG (DE) | 2002-03-13 | — | — | EP | disclosed |
| EP-0761681-A2 | Process for the preparation of substituted derivatives of N-ethylglycine | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-12 | — | — | EP | disclosed |