SCHEMBL752841

SCHEMBL752841

CCC(C)C1=CC(=O)NC1=O

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17924867 0.84 KDM4E (0.34)
SCHEMBL4162753 0.82
SCHEMBL17924959 0.81 GPR84 (0.34)
SCHEMBL9562487 0.80
SCHEMBL29575986 0.79
SCHEMBL29396273 0.79
SCHEMBL29018 0.78 EEF2K (0.38)
SCHEMBL4821010 0.78 LMNA (0.33)
SCHEMBL29104361 0.78
SCHEMBL1887395 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102409372-B Method of electroplating silver strike over nickel ROHM & HAAS ELECT MAT 2015-02-11 CN claimed
EP-2431501-B1 Method of electroplating silver strike over nickel ROHM & HAAS ELECT MAT (US) 2013-11-20 EP claimed
CN-102409372-A Method of electroplating silver strike over nickel ROHM & HAAS ELECT MAT 2012-04-11 CN claimed
US-20120067733-A1 METHOD OF ELECTROPLATING SILVER STRIKE OVER NICKEL ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2012-03-22 US claimed
EP-2431501-A1 Method of electroplating silver strike over nickel Rohm and Haas Electronic Materials LLC (US) 2012-03-21 EP claimed
WO-2024005126-A1 METHOD FOR PRODUCING N-ALKYLMALEIMIDE COPOLYMER AND N-ALKYLMALEIMIDE COPOLYMER 東ソー株式会社 2024-01-04 WO disclosed
US-11358940-B2 K-Ras modulators THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-06-14 US disclosed
US-20200247762-A1 K-RAS MODULATORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-08-06 US disclosed
CN-109415493-A Sealing material for semiconductor 太阳油墨制造株式会社 2019-03-01 CN disclosed
CN-105384865-B Optical resin material, the manufacturing method of the optical resin material, the optical resin component containing the material and the polarizing film containing the component 小池康博 2019-02-19 CN disclosed
CN-108627979-A Head-mounted display component 旭化成株式会社 2018-10-09 CN disclosed
CN-107230613-A The manufacture method of separating layer formation composition, lamilate and lamilate 东京应化工业株式会社 2017-10-03 CN disclosed
US-20110130318-A1 ENZYME COMPOSITION COMPRISING ENZYME CONTAINING POLYMER PARTICLES BASF SE (DE) 2011-06-02 US disclosed
EP-2310483-A1 ENZYME COMPOSITION COMPRISING ENZYME CONTAINING POLYMER PARTICLES BASF SE (DE) 2011-04-20 EP disclosed
WO-2010003934-A1 ENZYME COMPOSITION COMPRISING ENZYME CONTAINING POLYMER PARTICLES BASF SE (DE) 2010-01-14 WO disclosed
CN-1741993-A Process for producing cyclic amines NEW JAPAN CHEM CO LTD (JP) 2006-03-01 CN disclosed
EP-0393713-B1 Process for the preparation of N-substituted maleimides TOSOH CORP (JP) 1994-06-29 EP disclosed
US-5087705-A Heating N-substituted maleamic acid monoester in presence of acid catalyst SHIN-DAIKYOWA PETROCHEMICAL CO., LTD. (JP) 1992-02-11 US disclosed
EP-0393713-A1 Process for the preparation of N-substituted maleimides Tosoh Corporation (JP) 1990-10-24 EP disclosed
US-4246077-A SILVER COMPLEX OF 3-PYRROLINE-2,5-DIONE OR PYRROLIDINE-2,5-DIONE TECHNIC, INC. (US) 1981-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200247762-A1 K-RAS MODULATORS KRAS, HRAS, NRAS HDAC4 512/4885HDAC2 1166/4885HDAC8 426/4885
US-11358940-B2 K-Ras modulators KRAS, HRAS, NRAS HDAC4 1574/4885HDAC2 2172/4885HDAC8 1251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.