Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 4/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethiofencarb SCHEMBL74938 | 0.85 | ALDH1A1 (0.49) | TSHRACHEALDH1A1PGRGAA | |
| Ethiofencarb SCHEMBL6738022 | 0.85 | ALDH1A1 (0.49) | TSHRACHEALDH1A1PGRGAA | |
| Ethiofencarb SCHEMBL29449861 | 0.85 | ALDH1A1 (0.49) | TSHRACHEALDH1A1PGRGAA | |
| Ethiofencarb SCHEMBL7528780 | 0.84 | ALDH1A1 (0.46) | TSHRACHEALDH1A1PGRGAA | |
| SCHEMBL3634261 | 0.81 | ATM (0.47) | ACHEALDH1A1BCHENPC1RAB9A | |
| SCHEMBL11796469 | 0.79 | ALDH1A1 (0.46) | TSHRACHEALDH1A1PGRGAA | |
| Ethiofencarb SCHEMBL8382113 | 0.77 | ALDH1A1 (0.40) | TSHRACHEALDH1A1PGRGAA | |
| SCHEMBL11370599 | 0.75 | TSHR (0.43) | TSHRALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL10483081 | 0.74 | TSHR (0.38) | TSHRALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11590123 | 0.73 | TSHR (0.41) | TSHRALDH1A1HSD17B10BCHENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115025089-A | Application of cardiovascular medicine active ingredients, medicine and preparation method thereof | 中南大学湘雅医院 | 2022-09-09 | — | — | CN | disclosed |